Kent R B, Thomas L
Department of Surgical Education, Carraway Methodist Medical Center, Birmingham, Alabama 35234.
Am Surg. 1990 Jan;56(1):16-21.
Though surgeons have little input in the selection of patients for temporal-artery biopsy, a knowledge of temporal-artery anatomy and the pathophysiology of temporal arteritis is important. All temporal-artery biopsies done at Carraway Methodist Medical Center between January 1980 and January 1985 were reviewed. Seventy-three biopsies were performed on 70 patients and eight (11.4%) were found to have temporal arteritis histologically. One patient was judged to have temporal arteritis clinically, despite a negative biopsy of short length. Six of eight patients with positive biopsies were female, with an average age of 71.7 years. The most common signs and symptoms of those patients with positive biopsies were temporal headache (8/8), elevated erythrocyte sedimentation rate (7/8), temporal tenderness (5/8), jaw claudication (3/8), and visual changes (3/8). All biopsies were done under local anesthesia and there were no complications. With increasing awareness of the segmental nature of the disease, the length of biopsy specimens (formalin treated) increased from an average of 0.4 cm in 1980 to 2.4 cm in 1984. During this time, the positive rate increased from 0 per cent (0/9) to 17 per cent (4/24). A generous biopsy of approximately 5 cm in length of fresh vessel is recommended to confirm the suspected diagnosis of temporal arteritis.
虽然外科医生在颞动脉活检患者的选择上参与度不高,但了解颞动脉解剖结构和颞动脉炎的病理生理学很重要。回顾了1980年1月至1985年1月在卡拉韦卫理公会医疗中心进行的所有颞动脉活检。对70例患者进行了73次活检,其中8例(11.4%)经组织学检查发现患有颞动脉炎。1例患者临床诊断为颞动脉炎,尽管短长度活检结果为阴性。8例活检阳性的患者中有6例为女性,平均年龄71.7岁。活检阳性患者最常见的体征和症状是颞部头痛(8/8)、红细胞沉降率升高(7/8)、颞部压痛(5/8)、颌部间歇性运动障碍(3/8)和视力改变(3/8)。所有活检均在局部麻醉下进行,无并发症。随着对该病节段性本质认识的提高,活检标本(经福尔马林处理)的长度从1980年的平均0.4厘米增加到1984年的2.4厘米。在此期间,阳性率从0%(0/9)增加到17%(4/24)。建议对新鲜血管进行约5厘米长的充分活检,以确诊疑似颞动脉炎。