Área de Microbiología. Departamento Farmacia. Instituto de Ciencias Biomédicas. Facultad de Ciencias de la Salud, Universidad CEU Cardenal Herrera, Moncada Valencia, Spain.
Rev Med Virol. 2013 Nov;23(6):384-98. doi: 10.1002/rmv.1759. Epub 2013 Aug 28.
Acute hepatitis E is a very common disease in developing countries, to the point that, according to World Health Organization estimates, one third of the world's population has been exposed to HEV. It also causes outbreaks in refugee camps or after natural disasters such as floods or earthquakes. Sporadic cases of acute hepatitis have been observed in practically all European countries and other developed geographical areas, not only in travelers from endemic countries but also in people with no risk factors. But, lately, new aspects of this infection are appearing in industrialized countries such as the possibility of the disease becoming chronic in transplant patients, the immunocompromised in general, and even in patients with previous liver disease who are immunocompetent. In this comprehensive review, we summarize the current knowledge on HEV infection.
急性戊型肝炎在发展中国家非常常见，据世界卫生组织估计，全球有三分之一的人口曾感染过戊型肝炎病毒。它还会在难民营或洪水、地震等自然灾害后爆发。在几乎所有欧洲国家和其他发达地区都观察到了散发性急性肝炎病例，不仅在来自流行地区的旅行者中，而且在没有危险因素的人群中也有。但是，最近，这种感染在工业化国家出现了一些新的方面，例如在移植患者、一般免疫功能低下者，甚至在先前有肝脏疾病但免疫功能正常的患者中，该病可能会转为慢性。在这篇全面的综述中，我们总结了目前关于戊型肝炎病毒感染的知识。
