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农业基因组学在微藻生物燃料生产中的应用:综述各种生物信息学资源和近期将组学与生物能源和生物经济联系起来的研究。

Agrigenomics for microalgal biofuel production: an overview of various bioinformatics resources and recent studies to link OMICS to bioenergy and bioeconomy.

机构信息

1 Academy of Scientific and Innovative Research, CSIR-Institute of Minerals and Materials Technology , Bhubaneswar, Odisha, India .

出版信息

OMICS. 2013 Nov;17(11):537-49. doi: 10.1089/omi.2013.0025. Epub 2013 Sep 17.

Abstract

Microalgal biofuels offer great promise in contributing to the growing global demand for alternative sources of renewable energy. However, to make algae-based fuels cost competitive with petroleum, lipid production capabilities of microalgae need to improve substantially. Recent progress in algal genomics, in conjunction with other "omic" approaches, has accelerated the ability to identify metabolic pathways and genes that are potential targets in the development of genetically engineered microalgal strains with optimum lipid content. In this review, we summarize the current bioeconomic status of global biofuel feedstocks with particular reference to the role of "omics" in optimizing sustainable biofuel production. We also provide an overview of the various databases and bioinformatics resources available to gain a more complete understanding of lipid metabolism across algal species, along with the recent contributions of "omic" approaches in the metabolic pathway studies for microalgal biofuel production.

摘要

微藻生物燃料在满足全球对可再生能源替代资源不断增长的需求方面具有巨大的潜力。然而,为了使基于藻类的燃料在成本上具有与石油竞争的能力,微藻的产脂能力需要大幅提高。藻类基因组学的最新进展,结合其他“组学”方法,加速了鉴定代谢途径和基因的能力,这些途径和基因是开发具有最佳脂质含量的基因工程微藻菌株的潜在目标。在这篇综述中,我们总结了全球生物燃料原料的生物经济现状,特别提到了“组学”在优化可持续生物燃料生产中的作用。我们还概述了各种可用的数据库和生物信息学资源,以更全面地了解藻类物种的脂质代谢,并介绍了“组学”方法在微藻生物燃料生产代谢途径研究中的最新进展。

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