Department of Chemistry, University at Buffalo, The State University of New York, Amherst, NY 14260, USA.
Chem Commun (Camb). 2013 Nov 4;49(85):10025-7. doi: 10.1039/c3cc45000g.
The first examples of air-stable Co(II) paraCEST MRI contrast agents are reported. Amide NH protons on the complexes give rise to CEST peaks that are shifted up to 112 ppm from the bulk water resonance. One complex has multiple CEST peaks that may be useful for ratiometric mapping of pH.
首次报道了稳定的 Co(II) 顺磁 CEST MRI 对比剂的实例。配合物上的酰胺 NH 质子产生 CEST 峰，其从体相水共振峰位移高达 112 ppm。一种配合物具有多个 CEST 峰，这可能对 pH 的比率映射有用。
