ScHARR, University of Sheffield, Sheffield, UK.
BMJ Open. 2013 Sep 18;3(9):e003250. doi: 10.1136/bmjopen-2013-003250.
To estimate the cost-effectiveness of remote monitoring strategies versus usual care for adults recently discharged after a heart failure (HF) exacerbation.
Decision analysis modelling of cost-effectiveness using secondary data sources.
Acute hospitals in the UK.
Patients recently discharged (within 28 days) after a HF exacerbation.
Structured telephone support (STS) via human to machine (STS HM) interface, (2) STS via human to human (STS HH) contact and (3) home telemonitoring (TM), compared with (4) usual care.
The incremental cost per quality-adjusted life year (QALY) gained by each strategy compared to the next most effective alternative and the probability of each strategy being cost-effective at varying willingness to pay per QALY gained.
TM was the most cost-effective strategy in the scenario using these base case costs. Compared with usual care, TM had an estimated incremental cost effectiveness ratio (ICER) of £11 873/QALY, whereas STS HH had an ICER of £228 035/QALY against TM. STS HM was dominated by usual care. Threshold analysis suggested that the monthly cost of TM has to be higher than £390 to have an ICER greater than £20 000/QALY against STS HH. Scenario analyses performed using higher costs of usual care, higher costs of STS HH and lower costs of TM do not substantially change the conclusions.
Cost-effectiveness analyses suggest that TM was an optimal strategy in most scenarios, but there is considerable uncertainty in relation to clear descriptions of the interventions and robust estimation of costs.
评估远程监测策略相对于心力衰竭(HF)恶化后近期出院的成人常规护理的成本效益。
使用二级数据源进行成本效益的决策分析建模。
英国急性医院。
HF 恶化后近期出院(28 天内)的患者。
通过人机(STS HM)接口进行结构化电话支持(STS),(2)通过人与人(STS HH)接触进行 STS,(3)家庭远程监测(TM),与(4)常规护理相比。
与下一个更有效的替代方案相比,每种策略的增量成本每获得一个质量调整生命年(QALY),以及每种策略在不同的每获得一个 QALY 的意愿支付金额下具有成本效益的概率。
在使用这些基本成本的情况下,TM 是最具成本效益的策略。与常规护理相比,TM 的增量成本效果比(ICER)估计为 11873 英镑/QALY,而 STS HH 对 TM 的 ICER 为 228035 英镑/QALY。STS HM 被常规护理所主导。阈值分析表明,TM 的月成本必须高于 390 英镑,才能使 TM 相对于 STS HH 的 ICER 大于 20000 英镑/QALY。使用更高的常规护理成本、更高的 STS HH 成本和更低的 TM 成本进行的情景分析并没有实质性地改变结论。
成本效益分析表明,在大多数情况下,TM 是一种最优策略,但对于干预措施的明确描述和成本的稳健估计存在相当大的不确定性。