对丁香酚出现意外的阳性过敏反应。
An unexpected positive hypersensitive reaction to eugenol.
作者信息
Tammannavar Praveen, Pushpalatha C, Jain Shrenik, Sowmya S V
机构信息
Department of Orthodontics, BVP Dental College Sangli, Sangli, Maharahstra, India.
出版信息
BMJ Case Rep. 2013 Sep 18;2013:bcr2013009464. doi: 10.1136/bcr-2013-009464.
Eugenol is an active, principal aromatic liquid responsible for several pharmacological activities. It is widely used in dental practice to relieve pain arising from various sources, such as pulpitis and dentinal hypersensitivity. As a primary irritant and sensitiser, it is known to cause contact urticaria as well as chronic urticaria. However, eugenol causes allergic contact dermatitis, possibly because it can react directly with proteins to form conjugate and reactive haptens. It is found that eugenol in various dental preparations-especially in the case of some zinc oxide-contains preparations such as periodontal dressings and root canal cements. This can cause hypersensitivity when it comes in contact with gingiva or teeth. This article presents a case of immediate allergic contact urticaria to eugenol during dental treatment.
丁香酚是一种具有多种药理活性的活性主要芳香液体。它在牙科实践中被广泛用于缓解各种来源引起的疼痛，如牙髓炎和牙本质过敏。作为一种主要的刺激物和致敏剂，它已知会引起接触性荨麻疹以及慢性荨麻疹。然而，丁香酚会引起过敏性接触性皮炎，可能是因为它能直接与蛋白质反应形成共轭物和反应性半抗原。研究发现，各种牙科制剂中的丁香酚——尤其是在一些含氧化锌的制剂中，如牙周敷料和根管粘固剂中。当它与牙龈或牙齿接触时会引起过敏反应。本文介绍了一例牙科治疗期间对丁香酚立即发生过敏性接触性荨麻疹的病例。
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