Department of Psychiatry, Advanced Centre for Yoga, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
Indian J Psychiatry. 2013 Jul;55(Suppl 3):S369-73. doi: 10.4103/0019-5545.116312.
Therapeutic effects in depression of yoga adopted from different schools have been demonstrated. The efficacy of a generic module of yoga on depressed patients has not yet been tested in the literature.
The study was aimed to compare the therapeutic effect of a generic yoga module with antidepressant drugs in non-suicidal out-patients of major depression attending a psychiatric hospital.
The study was outpatient-based using an open-labeled design.
A total of 137 out-patients of depressive disorders received one of the three treatments as they chose - yoga-only, drugs-only or both. The yoga was taught by a trained yoga physician for over a month in spaced sessions totaling at least 12. Patients were assessed before treatment, after 1 and 3 months on depression and Clinical Global Impression Scales. Out of 137, 58 patients completed the study period with all assessments.
Patients in the three arms of treatment were comparable on demographic and clinical variables. Patients in all three arms of treatment obtained a reduction in depression scores as well as clinical severity. However, both yoga groups (with or without drugs) were significantly better than the drugs-only group. Higher proportion of patients remitted in the yoga groups compared with the drugs-only group. No untoward events were spontaneously reported in the yoga-treated patients.
Within the limitations of this study, it can be concluded that the findings support a case for prescribing yoga as taught in the study in depressive non-suicidal out-patients.
不同流派的瑜伽疗法在抑郁症中的疗效已得到证实。然而，文献中尚未测试过通用瑜伽模块对抑郁患者的疗效。
本研究旨在比较通用瑜伽模块与抗抑郁药物在精神科医院就诊的非自杀性抑郁症门诊患者中的治疗效果。
该研究采用开放标签设计，基于门诊。
共有 137 名抑郁症门诊患者根据自己的选择接受了三种治疗之一——仅瑜伽、仅药物或两者结合。瑜伽由经过培训的瑜伽医生教授，为期一个多月，间隔授课，总时长至少 12 小时。患者在治疗前、治疗后 1 个月和 3 个月接受抑郁和临床总体印象量表评估。在 137 名患者中，有 58 名完成了所有评估的研究期。
治疗的三个组别的患者在人口统计学和临床变量方面具有可比性。所有三组治疗的患者抑郁评分和临床严重程度均有所降低。然而，瑜伽组（无论是否联合药物治疗）均明显优于仅药物组。与仅药物组相比，瑜伽组中有更多的患者缓解。瑜伽治疗组的患者未自发报告不良事件。
在本研究的限制范围内，可以得出结论，研究结果支持在非自杀性抑郁症门诊患者中开具研究中教授的瑜伽处方。
