多种运动干预对心理健康障碍治疗的比较效果：一项系统评价和网状Meta分析
Comparative Effectiveness of Multiple Exercise Interventions in the Treatment of Mental Health Disorders: A Systematic Review and Network Meta-Analysis.
作者信息
Yu Qian, Wong Ka-Kit, Lei On-Kei, Nie Jinlei, Shi Qingde, Zou Liye, Kong Zhaowei
机构信息
Faculty of Education, University of Macau, Macao, China.
Faculty of Health Sciences and Sports, Macao Polytechnic University, Macao, China.
出版信息
Sports Med Open. 2022 Oct 29;8(1):135. doi: 10.1186/s40798-022-00529-5.
BACKGROUND
The efficacy of exercise interventions in the treatment of mental health disorders is well known, but research is lacking on the most efficient exercise type for specific mental health disorders.
OBJECTIVE
The present study aimed to compare and rank the effectiveness of various exercise types in the treatment of mental health disorders.
METHODS
The PubMed, Web of Science, PsycINFO, SPORTDiscus, CINAHL databases, and the Cochrane Central Register of Controlled Trials as well as Google Scholar were searched up to December 2021. We performed pairwise and network meta-analyses as well as meta-regression analyses for mental health disorders in general and each type of mental health disorder, with alterations in symptom severity as the primary outcome.
RESULTS
A total of 6456 participants from 117 randomized controlled trials were surveyed. The multimodal exercise (71%) had the highest probability of being the most efficient exercise for relieving depressive symptoms. While resistance exercise (60%) was more likely to be the most effective treatment for anxiety disorder, patients with post-traumatic stress disorder (PTSD) benefited more from mind-body exercise (52%). Furthermore, resistance exercise (31%) and multimodal exercise (37%) had more beneficial effects in the treatment of the positive and negative symptoms of schizophrenia, respectively. The length of intervention and exercise frequency independently moderated the effects of mind-body exercise on depressive (coefficient = 0.14, p = .03) and negative schizophrenia (coefficient = 0.96, p = .04) symptoms.
CONCLUSION
Multimodal exercise ranked best for treating depressive and negative schizophrenic symptoms, while resistance exercise seemed to be more beneficial for those with anxiety-related and positive schizophrenic symptoms. Mind-body exercise was recommended as the most promising exercise type in the treatment of PTSD. However, the findings should be treated with caution due to potential risk of bias in at least one dimension of assessment and low-to-moderate certainty of evidence. Trial Registration This systematic review was registered in the PROSPERO international prospective register of systematic reviews (CRD42022310237).
背景
运动干预对心理健康障碍的治疗效果已广为人知，但针对特定心理健康障碍最有效的运动类型的研究尚显不足。
目的
本研究旨在比较并排序各种运动类型在治疗心理健康障碍方面的有效性。
方法
检索了截至2021年12月的PubMed、科学网、PsycINFO、SPORTDiscus、CINAHL数据库、Cochrane对照试验中心注册库以及谷歌学术。我们对一般心理健康障碍和每种类型的心理健康障碍进行了成对和网状荟萃分析以及元回归分析，将症状严重程度的变化作为主要结局。
结果
共调查了来自117项随机对照试验的6456名参与者。多模式运动（71%）最有可能是缓解抑郁症状最有效的运动方式。而抗阻运动（60%）更有可能是治疗焦虑症最有效的方法，创伤后应激障碍（PTSD）患者从身心运动中获益更多（52%）。此外，抗阻运动（31%）和多模式运动（37%）分别对精神分裂症的阳性和阴性症状治疗有更有益的效果。干预时长和运动频率分别独立调节了身心运动对抑郁（系数 = 0.14，p = 0.03）和精神分裂症阴性（系数 = 0.96，p = 0.04）症状的影响。
结论
多模式运动在治疗抑郁和精神分裂症阴性症状方面排名最佳，而抗阻运动似乎对患有焦虑相关和精神分裂症阳性症状的患者更有益。身心运动被推荐为治疗PTSD最有前景的运动类型。然而，由于至少在一个评估维度上存在潜在的偏倚风险以及证据的确定性为低到中度，这些研究结果应谨慎对待。试验注册本系统评价已在PROSPERO国际前瞻性系统评价注册库（CRD42022310237）中注册。
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