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一个解释核电站附近儿童癌症的假说。

A hypothesis to explain childhood cancers near nuclear power plants.

机构信息

115 Riversdale Road, London N5 2SU, United Kingdom.

出版信息

J Environ Radioact. 2014 Jul;133:10-7. doi: 10.1016/j.jenvrad.2013.07.024. Epub 2013 Sep 19.

DOI:10.1016/j.jenvrad.2013.07.024
PMID:24054083
Abstract

Over 60 epidemiological studies world-wide have examined cancer incidences in children near nuclear power plants (NPPs): most of them indicate leukemia increases. These include the 2008 KiKK study commissioned by the German Government which found relative risks (RR) of 1.6 in total cancers and 2.2 in leukemias among infants living within 5 km of all German NPPs. The KiKK study has retriggered the debate as to the cause(s) of these increased cancers. A suggested hypothesis is that the increased cancers arise from radiation exposures to pregnant women near NPPs. However any theory has to account for the >10,000 fold discrepancy between official dose estimates from NPP emissions and observed increased risks. An explanation may be that doses from spikes in NPP radionuclide emissions are significantly larger than those estimated by official models which are diluted through the use of annual averages. In addition, risks to embryos/fetuses are greater than those to adults and haematopoietic tissues appear more radiosensitive in embryos/fetuses than in newborn babies. The product of possible increased doses and possible increased risks per dose may provide an explanation.

摘要

全球超过 60 项流行病学研究调查了核电站 (NPP) 附近儿童的癌症发病率:其中大多数表明白血病发病率增加。其中包括 2008 年由德国政府委托进行的 KiKK 研究,该研究发现,居住在距离所有德国 NPP 5 公里范围内的婴儿的总癌症相对风险 (RR) 为 1.6,白血病 RR 为 2.2。KiKK 研究重新引发了关于这些癌症增加原因的争论。一个假设是,这些癌症的增加是由于孕妇在 NPP 附近受到辐射暴露所致。然而,任何理论都必须解释官方 NPP 排放剂量估计值与观察到的风险增加之间超过 10000 倍的差异。一种解释可能是,NPP 放射性核素排放的峰值剂量明显大于官方模型估计的剂量,因为官方模型通过使用年平均值进行了稀释。此外,胚胎/胎儿的风险大于成年人,并且胚胎/胎儿中的造血组织比新生儿更敏感。可能增加的剂量和每剂量可能增加的风险的乘积可能提供了解释。

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