Fairlie Ian
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2010 Jan;28(1):1-21. doi: 10.1080/10590500903585366.
In 2008, the Kinderkrebs in der Umgebung von Kernkraftwerken (KiKK) study in Germany reported a 60% increase in solid cancers and a 120% increase in leukemias among children living within 5 km of all German nuclear power stations. The study has triggered debates as to the cause(s) of these increased cancers. This article reports on the findings of the KiKK study; discusses past and more recent epidemiological studies of leukemias near nuclear installations around the world, and outlines a possible biological mechanism to explain the increased cancers. This suggests that the observed high rates of infant leukemias may be a teratogenic effect from radionuclides incorporated by pregnant women living near nuclear reactors. Doses and risks from environmental emissions to embryos and fetuses may be larger than suspected. Hematopoietic tissues appear to be considerably more radiosensitive in embryos/fetuses than in newborn babies. Recommendations for advice to local residents and for further research are made.
2008年,德国的“核电站周边儿童癌症(KiKK)”研究报告称,居住在德国所有核电站周边5公里范围内的儿童,实体癌发病率增加了60%,白血病发病率增加了120%。该研究引发了关于这些癌症发病率上升原因的争论。本文报告了KiKK研究的结果;讨论了过去以及最近世界各地针对核设施附近白血病的流行病学研究,并概述了一种可能解释癌症发病率上升的生物学机制。这表明,观察到的婴儿白血病高发病率可能是居住在核反应堆附近的孕妇摄入放射性核素所产生的致畸效应。环境排放对胚胎和胎儿造成的剂量和风险可能比人们怀疑的要大。造血组织在胚胎/胎儿中似乎比在新生儿中对辐射更为敏感。本文还给出了针对当地居民的建议以及进一步研究的建议。