Department of Radiology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan,
Skeletal Radiol. 2014 Feb;43(2):257-61. doi: 10.1007/s00256-013-1727-z. Epub 2013 Sep 21.
Epidermoid cysts are epithelial cysts that present as slow-growing intradermal or subcutaneous lesions. While recent epidemiological studies have isolated human papillomavirus (HPV) from plantar epidermoid cysts, imaging findings in HPV-associated epidermoid cysts have not been previously reported. We describe imaging findings in two patients with HPV-associated plantar epidermoid cysts. Magnetic resonance (MR) imaging and ultrasonography (US) showed linear arrangement of several adjacent globular cysts. This appearance is hypothesized to result from HPV-associated eccrine duct metaplasia leading to cyst formation and later traumatic rupture leading to formation of multiple adjacent cystic components. It may be useful to suggest assessing the presence of HPV antigen in plantar lesions having these imaging findings.
表皮样囊肿是上皮性囊肿，表现为生长缓慢的真皮内或皮下病变。虽然最近的流行病学研究已经从足底表皮样囊肿中分离出人乳头瘤病毒 (HPV)，但 HPV 相关表皮样囊肿的影像学表现以前尚未报道。我们描述了 2 例 HPV 相关足底表皮样囊肿患者的影像学表现。磁共振成像 (MR) 和超声 (US) 显示多个相邻的球形囊肿呈线性排列。这种表现形式可能是由于 HPV 相关的外分泌管化生导致囊肿形成，随后外伤性破裂导致多个相邻囊性成分形成。对于具有这些影像学表现的足底病变，建议评估 HPV 抗原的存在可能会有所帮助。
