Egawa K, Kitasato H, Honda Y, Kawai S, Mizushima Y, Ono T
Department of Dermatology, Kumamoto University School of Medicine, Japan.
Br J Dermatol. 1998 Mar;138(3):510-4. doi: 10.1046/j.1365-2133.1998.02135.x.
We report a 23-year-old Japanese man who had plantar warts on the right sole, beneath one of which an epidermoid cyst developed. On microscopic examination, an acanthotic epidermis markedly invaginated into the underlying dermis, resulting in an open epidermoid cyst. Not only the polymerase chain reaction but also an in situ hybridization detected HPV 57 DNA in the cyst. HPV 60 is the only type of HPV that has been identified in epidermoid cysts. To our knowledge, this is the first case report of an epidermoid cyst, in which a different type of virus from HPV 60 was identified. Histological features of the cyst were also different those of HPV 60-associated epidermoid cysts.
我们报告一名23岁的日本男性，其右足底有跖疣，其中一个跖疣下方出现了表皮样囊肿。显微镜检查显示，棘层肥厚的表皮显著向下方真皮内凹陷，形成一个开放性表皮样囊肿。不仅聚合酶链反应，原位杂交也在囊肿中检测到了人乳头瘤病毒57型（HPV 57）DNA。HPV 60是唯一在表皮样囊肿中被鉴定出的HPV类型。据我们所知，这是首例报告的表皮样囊肿中鉴定出不同于HPV 60的病毒类型的病例。该囊肿的组织学特征也与HPV 60相关的表皮样囊肿不同。
