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儿童血管性皮肤异常:畸形与血管瘤

Vascular cutaneous anomalies in children: malformations and hemangiomas.

作者信息

Enjolras O, Mulliken J B

机构信息

Department of Dermatology, Pavillon Tarnier, Hôpital Cochin, 89 rue d'Assas, F-75006, Paris, France.

出版信息

Pediatr Surg Int. 1996 Jun;11(5-6):290-5. doi: 10.1007/BF00497795.

Abstract

The vast majority of cutaneous vascular anomalies in infants and children are either malformations or hemangiomas. Vascular malformations are subgrouped, based on channel morphology and rheology: slow-flow (capillary, lymphatic, venous, or combined-complex types) and fast-flow malformations (ectasia, aneurysm, fistula, or arteriovenous anomalies). Noninvasive radiologic techniques, especially ultrasonography with Doppler flow studies and magnetic resonance imaging, serve to document the extent and flow characteristics. Management depends on the type of malformation: laser for capillary malformations; surgical excision for lymphatic malformations; compression, sclerotherapy, and resection for venous malformations; and embolization and/or surgical resection for arteriovenous fistulae/malformations. Hemangiomas are the most common tumors of infancy. The life cycle is divided into three phases: proliferating, involuting, and involuted. Most hemangiomas do not require treatment, although drug therapy is indicated for endangering or life-threatening hemangiomas. Corticosteroids (either systemic or local) and alpha-2a interferon are currently the most effective agents. Surgical resection of problematic hemangiomas can be undertaken during infancy, the preschool years, or childhood.

摘要

婴幼儿皮肤血管异常绝大多数为畸形或血管瘤。血管畸形根据管道形态和流变学进行分组:低流速(毛细血管、淋巴管、静脉或复合型)和高流速畸形(扩张、动脉瘤、瘘管或动静脉畸形)。非侵入性放射学技术,尤其是多普勒血流研究超声检查和磁共振成像,用于记录病变范围和血流特征。治疗方法取决于畸形类型:毛细血管畸形采用激光治疗;淋巴管畸形采用手术切除;静脉畸形采用压迫、硬化治疗和切除;动静脉瘘/畸形采用栓塞和/或手术切除。血管瘤是婴儿期最常见的肿瘤。其生命周期分为三个阶段:增殖期、消退期和消退完成期。大多数血管瘤无需治疗,不过危及生命或有生命危险的血管瘤则需药物治疗。目前,皮质类固醇(全身或局部使用)和α-2a干扰素是最有效的药物。有问题的血管瘤可在婴儿期、学龄前或儿童期进行手术切除。

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