Arafah Maria Abdulrahim, Raddaoui Emad, Alsheikh Abdulmalik, Hajjar Waseem M, Alyousef Fatimah
Dr. Marial Abdulrahim Arafah, Depatment of Pathology,, King Saud University Colege of Medicine,, PO Box 800 Riyadh 11421, Saudi Arabia,
Ann Saudi Med. 2013 Jul-Aug;33(4):400-3. doi: 10.5144/0256-4947.2013.400.
Several reports have described different lung lesions mimicking primary or metastatic neoplasms. In this paper, we describe the different features of two uncommon and benign lung lesions mimicking metastasis from a primary large bowel adenocarcinoma. Our patient is a 75-year old female with a history of invasive rectal adenocarcinoma. One month after her surgery, she started complaining of coughing and shortness of breath. Clear cell sugar tumor and minute meningothelial-like nodules had been found incidentally and simultaneously during her chest x-ray. The diagnosis had been made based on morphology and was supported by a positive staining to a panel of immunohistochemical stains including CD34, vimentin, HMB45, melan A and S100. An ultra-structural examination was also performed and confirmed the presence of melanosomes in sugar tumor. The coexistence of lung sugar tumor and minute pulmonary meningothelial-like nodules has never been reported in the literature and an awareness of these lesions is essential to correctly diagnose and stage patients.
有几份报告描述了不同的肺部病变，这些病变酷似原发性或转移性肿瘤。在本文中，我们描述了两种罕见的良性肺部病变的不同特征，它们酷似原发性大肠腺癌的转移瘤。我们的患者是一名75岁女性，有浸润性直肠腺癌病史。她手术后一个月开始抱怨咳嗽和气短。在胸部X光检查时偶然同时发现了透明细胞糖瘤和微小脑膜上皮样结节。诊断基于形态学，并通过对包括CD34、波形蛋白、HMB45、黑素A和S100在内的一组免疫组织化学染色呈阳性得到支持。还进行了超微结构检查，证实糖瘤中存在黑素小体。肺部糖瘤和微小肺脑膜上皮样结节并存的情况在文献中从未有过报道，认识这些病变对于正确诊断和对患者进行分期至关重要。
