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肺透明细胞“糖”瘤:一例报告并文献复习

Clear cell "sugar" tumor of the lung: a case report and review of the literature.

作者信息

Chang Matthew, Lim Derek, Genovesi Mark

机构信息

St. George's University School of Medicine, West Indies, Grenada.

Department of Cardiothoracic Surgery, NYU Langone - Brooklyn, NY, USA.

出版信息

AME Case Rep. 2018 Aug 24;2:40. doi: 10.21037/acr.2018.08.03. eCollection 2018.

DOI:10.21037/acr.2018.08.03
PMID:30363768
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6182013/
Abstract

Clear cell "sugar" tumor of the lung is a rare benign tumor that is often an incidental finding during histopathologic workup. It strikingly has a similar resemblance to renal cell carcinoma (RCC) cells. Under the microscope, it is composed of thin cell walls and high levels of glycogen. Therefore, when diagnosed, it is important to rule out metastatic RCC. Here, in this case report, we present a case of clear cell "sugar" tumor of the lung and review the literature that has been published. Clear cell tumor of the lung needs to be studied more extensively as it can present with unique signs and symptoms. It has also occurred in the presence of systemic diseases. This has led researchers to theorize about its etiology which we discuss in this case report.

摘要

肺透明细胞“糖”瘤是一种罕见的良性肿瘤,常在组织病理学检查时偶然发现。它与肾细胞癌(RCC)细胞有着惊人的相似之处。在显微镜下,它由薄壁细胞和高水平的糖原组成。因此,在诊断时,排除转移性RCC很重要。在此病例报告中,我们呈现了一例肺透明细胞“糖”瘤病例并回顾已发表的文献。肺透明细胞肿瘤需要更广泛地研究,因为它可能表现出独特的体征和症状。它也在全身性疾病的情况下发生。这促使研究人员对其病因进行理论推测,我们将在本病例报告中进行讨论。

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本文引用的文献

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Mimicry of sugar tumor and minute pulmonary meningothelial-like nodule to metastatic lung deposits in a patient with rectal adenocarcinoma.一名直肠癌患者中糖瘤和微小肺脑膜上皮样结节酷似肺转移瘤。
Ann Saudi Med. 2013 Jul-Aug;33(4):400-3. doi: 10.5144/0256-4947.2013.400.
2
Lung Clear "Sugar" Cell Tumor and JAK V617F Positive Essential Thrombocythemia: a Simple Coincidence?肺透明细胞“糖”细胞瘤和 JAK V617F 阳性原发性血小板增多症:单纯巧合?
Mediterr J Hematol Infect Dis. 2013 Apr 10;5(1):e2013021. doi: 10.4084/MJHID.2013.021. Print 2013.
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Malignant clear cell sugar tumor of the lung: patient case report.肺恶性透明细胞糖瘤:病例报告
J Clin Oncol. 2010 Nov 1;28(31):e626-8. doi: 10.1200/JCO.2010.29.6939. Epub 2010 Aug 30.
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PEComa (clear cell "sugar" tumor) of the lung: a benign tumor that presented with thrombocytosis.肺透明细胞“糖”瘤(PEComa):一种表现为血小板增多症的良性肿瘤。
Ann Thorac Surg. 2009 Dec;88(6):2013-5. doi: 10.1016/j.athoracsur.2009.05.041.
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Large clear cell tumor of the lung mimicking malignant behavior.酷似恶性行为的肺大透明细胞瘤。
Ann Thorac Surg. 2007 Jan;83(1):310-2. doi: 10.1016/j.athoracsur.2006.04.038.
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A rare cause of hemoptysis: benign sugar (clear) cell tumor of the lung.咯血的罕见病因:肺良性透明细胞瘤。
Eur J Cardiothorac Surg. 2004 Apr;25(4):652-4. doi: 10.1016/j.ejcts.2004.01.022.
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Primary extrapulmonary sugar tumor (PEST): a report of four cases.原发性肺外糖瘤(PEST):4例报告
Mod Pathol. 2001 Jun;14(6):615-22. doi: 10.1038/modpathol.3880360.
8
Regional proliferation of HMB-45-positive clear cells of the lung with lymphangioleiomyomatosislike distribution, replacing the lobes with multiple cysts and a nodule.肺内HMB-45阳性透明细胞呈淋巴管平滑肌瘤样分布的区域增殖,多个囊肿和一个结节取代了肺叶。
Am J Surg Pathol. 1999 Oct;23(10):1288-93. doi: 10.1097/00000478-199910000-00016.
9
Clear cell "sugar" tumor of the lung: association with lymphangioleiomyomatosis and multifocal micronodular pneumocyte hyperplasia in a patient with tuberous sclerosis.肺透明细胞“糖”瘤:与结节性硬化症患者的淋巴管平滑肌瘤病及多灶性微小结节性肺细胞增生相关
Am J Surg Pathol. 1997 Oct;21(10):1242-7. doi: 10.1097/00000478-199710000-00017.
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