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大麻与交通事故风险:一项基于伤患司机就诊于急诊室的病例交叉研究结果。

Cannabis and traffic collision risk: findings from a case-crossover study of injured drivers presenting to emergency departments.

机构信息

Department of Community Health and Epidemiology, Centre for Clinical Research, Dalhousie University, 4th Floor, 5790 University Avenue, Halifax, NS, B3H 1V7, Canada,

出版信息

Int J Public Health. 2014 Apr;59(2):395-404. doi: 10.1007/s00038-013-0512-z. Epub 2013 Sep 24.

Abstract

OBJECTIVES

This study examined whether acute cannabis use leads to an increased collision risk.

METHODS

Participants were 860 drivers presenting to emergency departments in Toronto and Halifax, Canada, with an injury from a traffic collision, between April 2009 and July 2011. Cannabis and other drug use were identified either through blood sample or self-report. A case-crossover design was employed with two control conditions: a fixed condition measuring substance use during last time driving, and whether the driver typically uses cannabis prior to driving. Collision risk was assessed through conditional fixed-effects logistic regression models.

RESULTS

Results revealed that 98 (11 %; 95 % CI: 9.0-13.1) drivers reported using cannabis prior to the collision. Regression results measuring exposure with blood and self-report data indicated that cannabis use alone was associated with a fourfold increased (OR 4.11; 95 % CI: 1.98-8.52) odds of a collision; a regression relying on self-report measures only found no significant association.

CONCLUSIONS

Main findings confirmed that cannabis use increases collision risk and reinforces existing policy and educational efforts, in many high-income countries, aimed at reducing driving under the influence of cannabis.

摘要

目的

本研究旨在探究急性大麻使用是否会增加碰撞风险。

方法

参与者为 2009 年 4 月至 2011 年 7 月期间,在加拿大多伦多和哈利法克斯的急诊部门因交通碰撞受伤的 860 名驾驶员。大麻和其他药物的使用情况通过血液样本或自我报告确定。采用病例交叉设计,有两种对照条件:固定条件衡量上次驾驶时的物质使用情况,以及驾驶员在驾驶前是否通常使用大麻。碰撞风险通过条件固定效应逻辑回归模型进行评估。

结果

结果显示,98 名(11%;95%置信区间:9.0-13.1)驾驶员报告在碰撞前使用了大麻。使用血液和自我报告数据测量暴露的回归结果表明,单独使用大麻与碰撞风险增加四倍相关(OR 4.11;95%置信区间:1.98-8.52);仅依靠自我报告测量的回归未发现显著关联。

结论

主要发现证实了大麻使用会增加碰撞风险,并加强了许多高收入国家现有的政策和教育努力,旨在减少大麻影响下的驾驶。

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