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在墨西哥韦拉克鲁斯中部的一个一级诊所中,对低危人群的尿液样本进行 PCR 法同时检测阴道毛滴虫和白色念珠菌。

Codetection of Trichomonas vaginalis and Candida albicans by PCR in urine samples in a low-risk population attended in a clinic first level in central Veracruz, Mexico.

机构信息

LADISER Inmunología y Biología Molecular, Facultad de Ciencias Químicas, Universidad Veracruzana, 94340 Orizaba, VER, Mexico ; Centro de Investigaciones Biomédicas, Universidad Veracruzana, 91000 Xalapa, VER, Mexico.

出版信息

Biomed Res Int. 2013;2013:281892. doi: 10.1155/2013/281892. Epub 2013 Aug 29.

Abstract

The aim of this study is to estimate the prevalence of Trichomonas vaginalis and Candida albicans in low-risk patients treated at a first level clinic (primary health care represents the first level of contact of individuals, families, and the community with the system national health). Using a cross-sectional study in patients treated in clinical laboratory of the Sanitary District no. 7 of the city of Orizaba during the months June-July, 252 urine samples were collected for the identification of T. vaginalis and C. albicans by PCR. Furthermore, we analyzed the sociodemographic characteristics of the studied population. We observed an overall prevalence of 23.41% (95% CI 22.10-24.72) for T. vaginalis and 38.88% (95% CI 37.73-40.03) for C. albicans. There was also presence of coinfection in 14.28% (95% CI 13.10-15.46), which was associated with the presence of pain. Most of the positive cases were observed in women house-maker (80%, 95% CI 50.36-48.98). The results of this study provide evidence that the majority of positive cases observed in the studied population are presented in an asymptomatic form and usually are not associated with any risk factor.

摘要

本研究旨在估计在一级诊所(初级卫生保健代表个人、家庭和社区与国家卫生系统的第一级接触)治疗的低危患者中阴道毛滴虫和白色念珠菌的患病率。在 6 月至 7 月期间,通过聚合酶链反应(PCR)对来自奥里萨巴市第 7 卫生区临床实验室治疗的患者的 252 份尿液样本进行了阴道毛滴虫和白色念珠菌的鉴定,并采用横断面研究方法。此外,我们分析了研究人群的社会人口统计学特征。我们观察到阴道毛滴虫的总患病率为 23.41%(95%置信区间 22.10-24.72),白色念珠菌的总患病率为 38.88%(95%置信区间 37.73-40.03)。在 14.28%(95%置信区间 13.10-15.46)的患者中也存在混合感染,这与疼痛的存在有关。大多数阳性病例发生在家庭主妇中(80%,95%置信区间 50.36-48.98)。本研究结果表明,在研究人群中观察到的大多数阳性病例呈无症状形式,且通常与任何危险因素无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f9/3773406/1f5313fa4167/BMRI2013-281892.001.jpg

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