Wey Hsiao-Ying, Desai Virendra R, Duong Timothy Q
University of Texas Health Science Center, San Antonio, Texas, USA.
Neurol Res. 2013 Dec;35(10):1092-102. doi: 10.1179/1743132813Y.0000000250. Epub 2013 Aug 16.
Stroke is a serious healthcare problem with high mortality and long-term disability. However, to date, our ability to prevent and cure stroke remains limited. One important goal in stroke research is to identify the extent and location of lesion for treatment. In addition, accurately differentiating salvageable tissue from infarct and evaluating therapeutic efficacies are indispensible. These objectives could potentially be met with the assistance of modern neuroimaging techniques. This paper reviews current imaging methods commonly used in ischemic stroke research. These methods include positron emission tomography, computed tomography, T1 MRI, T2 MRI, diffusion and perfusion MRI, diffusion tensor imaging, blood-brain barrier permeability MRI, pH-weighted MRI, and functional MRI.
中风是一个严重的医疗保健问题，具有高死亡率和长期残疾率。然而，迄今为止，我们预防和治疗中风的能力仍然有限。中风研究的一个重要目标是确定病变的范围和位置以进行治疗。此外，准确区分可挽救组织与梗死组织并评估治疗效果是必不可少的。借助现代神经成像技术有可能实现这些目标。本文综述了目前在缺血性中风研究中常用的成像方法。这些方法包括正电子发射断层扫描、计算机断层扫描、T1磁共振成像、T2磁共振成像、扩散和灌注磁共振成像、扩散张量成像、血脑屏障通透性磁共振成像、pH加权磁共振成像和功能磁共振成像。
