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一种针对引产球囊在临产前反应的简化子宫颈模型。

A simplified cervix model in response to induction balloon in pre-labour.

作者信息

Smith James Andrew

机构信息

Department of Electrical & Computer Engineering, Ryerson University, Toronto, Canada.

出版信息

Theor Biol Med Model. 2013 Sep 26;10:58. doi: 10.1186/1742-4682-10-58.

Abstract

BACKGROUND

Induction of labour is poorly understood even though it is performed in 20% of births in the United States. One method of induction, the balloon dilator applied with traction to the interior os of the cervix, engages a softening process, permitting dilation and effacement to proceed until the beginning of active labour. The purpose of this work is to develop a simple model capable of reproducing the dilation and effacement effect in the presence of a balloon.

METHODS

The cervix, anchored by the uterus and the endopelvic fascia was modelled in pre-labour. The spring-loaded, double sliding-joint, double pin-joint mechanism model was developed with a Modelica-compatible system, MapleSoft MapleSim 6.1, with a stiff Rosenbrock solver and 1E-4 absolute and relative tolerances. Total simulation time for pre-labour was seven hours and simulations ended at 4.50 cm dilation diameter and 2.25 cm effacement.

RESULTS

Three spring configurations were tested: one pin joint, one sliding joint and combined pin-joint-sliding-joint. Feedback, based on dilation speed modulated the spring values, permitting controlled dilation. Dilation diameter speed was maintained at 0.692 cm·hr-1 over the majority of the simulation time. In the sliding-joint-only mode the maximum spring constant value was 23800 N·m-1. In pin-joint-only the maximum spring constant value was 0.41 N·m·rad-1. With a sliding-joint-pin-joint pair the maximum spring constants are 2000 N·m-1 and 0.41 N·m·rad-1, respectively.

CONCLUSIONS

The model, a simplified one-quarter version of the cervix, is capable of maintaining near-constant dilation rates, similar to published clinical observations for pre-labour. Lowest spring constant values are achieved when two springs are used, but nearly identical tracking of dilation speed can be achieved with only a pin joint spring. Initial and final values for effacement and dilation also match published clinical observations. These results provide a framework for development of electro-mechanical phantoms for induction training, as well as dilator testing and development.

摘要

背景

尽管在美国20%的分娩中会进行引产,但人们对引产的了解却很少。一种引产方法是将球囊扩张器施加牵引力于子宫颈内口,引发软化过程,使宫颈扩张和消退得以进行,直至进入活跃分娩期。这项工作的目的是开发一个简单模型,能够在有球囊的情况下重现宫颈扩张和消退的效果。

方法

将由子宫和盆腔内筋膜固定的宫颈在分娩前进行建模。使用MapleSoft MapleSim 6.1开发了弹簧加载、双滑动关节、双销关节机制模型,该系统与Modelica兼容,采用刚性罗森布罗克求解器,绝对和相对容差为1E - 4。分娩前的总模拟时间为7小时,模拟在扩张直径达到4.50厘米和消退达到2.25厘米时结束。

结果

测试了三种弹簧配置:一个销关节、一个滑动关节以及销关节 - 滑动关节组合。基于扩张速度的反馈调节弹簧值,实现可控扩张。在大部分模拟时间内,扩张直径速度保持在0.692厘米·小时⁻¹。在仅滑动关节模式下,最大弹簧常数为23800牛·米⁻¹。在仅销关节模式下,最大弹簧常数为0.41牛·米·弧度⁻¹。对于滑动关节 - 销关节对,最大弹簧常数分别为2000牛·米⁻¹和0.41牛·米·弧度⁻¹。

结论

该模型是宫颈的简化四分之一版本,能够保持接近恒定的扩张速率,类似于已发表的分娩前临床观察结果。使用两个弹簧时弹簧常数最低,但仅使用销关节弹簧也能实现几乎相同的扩张速度跟踪。消退和扩张的初始值及最终值也与已发表的临床观察结果相符。这些结果为开发用于引产训练以及扩张器测试和开发的机电模型提供了框架。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e54/3850663/ddbb153800d4/1742-4682-10-58-1.jpg

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