Podell Michael
Chicago Veterinary Neurology and Neurosurgery, Chicago Veterinary Emergency and Specialty Center, Chicago, IL, USA.
Top Companion Anim Med. 2013 May;28(2):59-66. doi: 10.1053/j.tcam.2013.06.009.
Over the past 2 decades, the number of antiepileptic drugs (AEDs) available to veterinarians has grown exponentially. Coupled with this increase is the ability to rapidly and accurately diagnose underlying brain disease with readily accessible magnetic resonance imaging. As a result, the veterinary community is attuned to the need for early treatment intervention. As more treatment choices become available, the unrelenting questions still arise are when should treatment begin, which initial drug therapy is best for our patients, when should treatment changes be considered, and finally, what are the advantages that newer drugs provide for our patients. The purpose of this chapter is to review decision-making strategies for AED therapy, provide an overview of the applicability of current AED available, and present information on the therapeutic advances in epilepsy.
在过去20年里,兽医可用的抗癫痫药物(AEDs)数量呈指数级增长。与此同时,利用易于获得的磁共振成像能够快速、准确地诊断潜在脑部疾病。因此,兽医界认识到早期治疗干预的必要性。随着更多治疗选择的出现,一些一直存在的问题仍然存在:治疗应何时开始,哪种初始药物治疗对我们的患者最有利,何时应考虑改变治疗方案,以及最后,新药能为我们的患者带来哪些优势。本章的目的是回顾AED治疗的决策策略,概述现有AED的适用性,并介绍癫痫治疗方面的进展。