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猫的癫痫发作与癫痫

Seizures and epilepsy in cats.

作者信息

Moore Sarah A

机构信息

Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH, USA.

出版信息

Vet Med (Auckl). 2014 Jul 30;5:41-47. doi: 10.2147/VMRR.S62077. eCollection 2014.

DOI:10.2147/VMRR.S62077
PMID:32670845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7337200/
Abstract

Seizures are a common presenting complaint in cats, although causes and options for the treatment of seizures in this species have been historically poorly described in the veterinary literature. Seizure manifestation in cats may be different than what is typically seen in dogs, but the underlying causes of seizure activity are the same. These include primary epilepsies, structural epilepsies, and reactive seizures. Although primary epilepsy was once believed to be rare in cats, we now commonly appreciate this syndrome, albeit at a lower frequency than in dogs. Because of this, a complete diagnostic work-up is recommended for all cats presenting for initial evaluation of seizures. Symptomatic treatment of seizures in cats is similar to dogs, with only a few limitations related to species-specific antiepileptic drug toxicities. The goal of this review is to summarize the recent veterinary literature related to feline seizures, with a focus on seizure classification, clinical manifestation, diagnostic evaluation, and treatment options.

摘要

癫痫发作是猫常见的就诊主诉,尽管该物种癫痫发作的病因及治疗选择在兽医文献中历来描述甚少。猫的癫痫发作表现可能与犬类常见的表现不同,但癫痫活动的潜在病因是相同的。这些病因包括原发性癫痫、结构性癫痫和反应性癫痫。虽然原发性癫痫曾被认为在猫中罕见,但我们现在普遍认识到这种综合征,尽管其发生频率低于犬类。因此,对于所有因癫痫发作进行初次评估的猫,建议进行全面的诊断检查。猫癫痫发作的对症治疗与犬类相似,只是在特定物种抗癫痫药物毒性方面存在一些限制。本综述的目的是总结近期与猫癫痫发作相关的兽医文献,重点关注癫痫发作的分类、临床表现、诊断评估和治疗选择。

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Seizures and epilepsy in cats.猫的癫痫发作与癫痫
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2
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Antiepileptic drug therapy.抗癫痫药物治疗
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A single-blinded phenobarbital-controlled trial of levetiracetam as mono-therapy in dogs with newly diagnosed epilepsy.一项关于左乙拉西坦作为新诊断癫痫犬单药治疗的单盲、苯巴比妥对照试验。
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引用本文的文献

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Survival Outcomes and Predictive Factors of Mortality in Feline Epilepsy: A Comprehensive Retrospective Study.猫癫痫的生存结局及死亡预测因素:一项全面的回顾性研究。
Animals (Basel). 2025 May 22;15(11):1504. doi: 10.3390/ani15111504.
2
Emergency Approach to Acute Seizures in Dogs and Cats.犬猫急性癫痫发作的急救方法
Vet Sci. 2024 Jun 17;11(6):277. doi: 10.3390/vetsci11060277.
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A retrospective study of the efficacy of zonisamide in controlling seizures in 57 cats.一项回顾性研究评估了左乙拉西坦控制 57 例猫癫痫发作的疗效。
J Vet Intern Med. 2024 Mar-Apr;38(2):1092-1100. doi: 10.1111/jvim.16984. Epub 2024 Jan 19.
4
Questionnaire survey on the usage of antiseizure drugs for dogs and cats in Japanese veterinary hospitals (2020).日本兽医医院犬猫抗癫痫药物使用情况问卷调查(2020 年)。
Vet Med Sci. 2022 Jul;8(4):1466-1471. doi: 10.1002/vms3.810. Epub 2022 Apr 20.
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Feline temporal lobe epilepsy: seven cases of hippocampal and piriform lobe necrosis in England and literature review.猫颞叶癫痫:英国七例海马和梨状回坏死病例及文献复习。
J Feline Med Surg. 2022 Jun;24(6):596-608. doi: 10.1177/1098612X211035049. Epub 2021 Aug 6.

本文引用的文献

1
Classics in chemical neuroscience: diazepam (valium).经典神经化学:地西泮(安定)。
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Clinical characterization of epilepsy of unknown cause in cats.猫特发性癫痫的临床特征
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Antiepileptic drug therapy and monitoring.抗癫痫药物治疗与监测
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A clinical and diagnostic approach to the patient with seizures.癫痫患者的临床与诊断方法
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Terminology and classification of seizures and epilepsy in veterinary patients.兽医患者癫痫发作和癫痫的术语与分类
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Complex partial orofacial seizures in English cats.英国短毛猫的复杂部分性口面部癫痫发作
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9
Renal tubular acidosis associated with zonisamide therapy in a dog.一只犬因唑尼沙胺治疗出现肾小管性酸中毒。
J Vet Intern Med. 2011 Nov-Dec;25(6):1454-7. doi: 10.1111/j.1939-1676.2011.00801.x. Epub 2011 Sep 21.
10
Apparent acute idiosyncratic hepatic necrosis associated with zonisamide administration in a dog.一只犬服用唑尼沙胺后出现明显的急性特发性肝坏死。
J Vet Intern Med. 2011 Sep-Oct;25(5):1156-60. doi: 10.1111/j.1939-1676.2011.00783.x. Epub 2011 Aug 30.