2008-2010 年美国年轻成年女性人乳头瘤病毒疫苗接种率的地域差异。
Geographic variation in human papillomavirus vaccination uptake among young adult women in the United States during 2008-2010.
机构信息
Department of Obstetrics and Gynecology and the Center for Interdisciplinary Research in Women's Health, University of Texas Medical Branch, Galveston, Texas, United States.
出版信息
Vaccine. 2013 Nov 12;31(47):5495-9. doi: 10.1016/j.vaccine.2013.09.022. Epub 2013 Sep 23.
Abstract
Very little is known about geographic variation in human papillomavirus (HPV) vaccine uptake among young adult women in the US. To investigate this, we analyzed data from 12 US states collected through the Behavioral Risk Factor Surveillance System between 2008 and 2010. Among 2632 young adult women (18-26 years old) who responded to HPV vaccine uptake questions, weighted vaccine initiation and completion rates were: 28.0% and 17.0% overall, 14.0% and 6.6% in the South, 28.7% and 19.3% in the Midwest/West, and 37.2% and 23.1% in the Northeast (P<0.001), respectively. Log-binomial regression analysis showed that women living in the South were less likely to initiate (adjusted prevalence ratio (aPR) 0.71, 95% confidence interval (CI) 0.60-0.83) or complete (aPR 0.61, 95% CI, 0.53-0.71) the HPV vaccine series compared to women living in the Northeast. Interventions programs to improve HPV vaccine uptake in the Southern states are warranted.
摘要
关于美国年轻成年女性中 HPV 疫苗接种的地理差异，人们知之甚少。为了调查这一点，我们分析了 2008 年至 2010 年期间通过行为风险因素监测系统在美国 12 个州收集的数据。在回答 HPV 疫苗接种问题的 2632 名年轻成年女性（18-26 岁）中，加权疫苗接种起始率和完成率分别为：总体 28.0%和 17.0%，南部为 14.0%和 6.6%，中西部/西部为 28.7%和 19.3%，东北部为 37.2%和 23.1%（P<0.001）。对数二项式回归分析显示，与居住在东北部的女性相比，居住在南部的女性更不可能开始（调整后的流行率比（aPR）0.71，95%置信区间（CI）0.60-0.83）或完成（aPR 0.61，95%CI，0.53-0.71）HPV 疫苗系列。有必要在南部各州开展干预计划以提高 HPV 疫苗接种率。
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