Fenton A C, Evans D H, Levene M I
Leicester University School of Medicine, Department of Child Health.
Arch Dis Child. 1990 Jan;65(1 Spec No):11-4. doi: 10.1136/adc.65.1_spec_no.11.
To test the hypothesis that impairment of cerebral perfusion and cerebrovascular autoregulation play a part in the pathogenesis of neurological injury in the critically sick neonate, we tested in 33 infants a small, light-weight probe and cable that are attached to the infant's skin to record cerebral blood flow velocity from the middle cerebral artery over a period of hours. This considerably reduced the amount of handling of the infant compared with conventional assessment. Captured data were analysed and displayed graphically at the cotside. The system is applicable for use on infants over a wide range of gestational ages and may give information on the complex haemodynamic changes occurring in the cerebral circulation.
为了验证脑灌注受损和脑血管自动调节在危重新生儿神经损伤发病机制中起作用这一假说,我们对33名婴儿进行了测试,使用一个小型、轻便的探头和电缆,将其附着在婴儿皮肤上,在数小时内记录大脑中动脉的脑血流速度。与传统评估相比,这大大减少了对婴儿的操作次数。采集到的数据在床边进行分析并以图形方式显示。该系统适用于广泛孕周的婴儿,可能会提供有关脑循环中发生的复杂血流动力学变化的信息。