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Determining Genotypic Drug Resistance by Ion Semiconductor Sequencing With the Ion AmpliSeq™ TB Panel in Multidrug-Resistant Mycobacterium tuberculosis Isolates.应用 Ion AmpliSeq™ TB Panel 通过离子半导体测序技术检测耐多药结核分枝杆菌分离株的基因型耐药性。
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Next-generation ion torrent sequencing of drug resistance mutations in Mycobacterium tuberculosis strains.结核分枝杆菌耐药突变的下一代离子激流测序。
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Comparison of the socio-demographic and clinical features of pulmonary TB patients infected with sub-lineages within the W-Beijing and non-Beijing Mycobacterium tuberculosis.W-北京型和非北京型结核分枝杆菌亚谱系感染的肺结核患者的社会人口学和临床特征比较
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Extensively drug-resistant tuberculosis in Myanmar: burden and mutations causing second-line drug resistance.缅甸广泛耐药结核病：二线药物耐药相关的负担和突变。
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First genetic characterisation of multidrug-resistant Mycobacterium tuberculosis isolates from Algeria.首次对来自阿尔及利亚的耐多药结核分枝杆菌分离株进行基因特征分析。
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Phenotypic and molecular characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates in Ningbo, China.中国宁波耐多药结核分枝杆菌分离株中吡嗪酰胺耐药的表型和分子特征。
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Whole-genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates from Myanmar.缅甸耐多药结核分枝杆菌分离株的全基因组测序。
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Targeted next-generation sequencing to diagnose drug-resistant tuberculosis: a systematic review and meta-analysis.靶向二代测序诊断耐多药结核病：一项系统评价与荟萃分析
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Current and Future Technologies for the Detection of Antibiotic-Resistant Bacteria.检测抗生素耐药细菌的当前及未来技术
Diagnostics (Basel). 2023 Oct 18;13(20):3246. doi: 10.3390/diagnostics13203246.
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A bioinformatics pipeline for Mycobacterium tuberculosis sequencing that cleans contaminant reads from sputum samples.结核分枝杆菌测序的生物信息学分析流程，可清除痰样本中的污染读取。
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Compatibility of a novel filter paper-based bio-safe sputum transport kit with line probe assay for diagnosing drug-resistant tuberculosis: a single-site evaluation study.一种新型基于滤纸的生物安全痰标本转运试剂盒与用于诊断耐多药结核病的线性探针检测法的兼容性：单中心评估研究
ERJ Open Res. 2021 Aug 2;7(3). doi: 10.1183/23120541.00137-2021. eCollection 2021 Jul.
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Validation of Novel Mycobacterium tuberculosis Isoniazid Resistance Mutations Not Detectable by Common Molecular Tests.新型结核分枝杆菌异烟肼耐药突变的验证，这些突变不能通过常见的分子检测方法检出。
Antimicrob Agents Chemother. 2018 Sep 24;62(10). doi: 10.1128/AAC.00974-18. Print 2018 Oct.
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Determining Genotypic Drug Resistance by Ion Semiconductor Sequencing With the Ion AmpliSeq™ TB Panel in Multidrug-Resistant Mycobacterium tuberculosis Isolates.应用 Ion AmpliSeq™ TB Panel 通过离子半导体测序技术检测耐多药结核分枝杆菌分离株的基因型耐药性。
Ann Lab Med. 2018 Jul;38(4):316-323. doi: 10.3343/alm.2018.38.4.316.
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Next-Generation Sequencing for Characterizing Drug Resistance-Conferring Mycobacterium tuberculosis Genes from Clinical Isolates in the Ukraine.从乌克兰临床分离株中鉴定耐药相关结核分枝杆菌基因的下一代测序。
J Clin Microbiol. 2018 May 25;56(6). doi: 10.1128/JCM.00009-18. Print 2018 Jun.
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The diagnostic utility of line probe assays for multidrug-resistant tuberculosis.线探针检测对耐多药结核病的诊断效用
Pathog Glob Health. 2016 Jun-Jul;110(4-5):194-9. doi: 10.1080/20477724.2016.1214350. Epub 2016 Aug 8.
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Antibiotic resistance mechanisms of Myroides sp.食酸菌属细菌的抗生素耐药机制
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Emerging rapid resistance testing methods for clinical microbiology laboratories and their potential impact on patient management.临床微生物实验室新兴的快速耐药性检测方法及其对患者管理的潜在影响。
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本文引用的文献
1
Next-generation ion torrent sequencing of drug resistance mutations in Mycobacterium tuberculosis strains.结核分枝杆菌耐药突变的下一代离子激流测序。
J Clin Microbiol. 2012 Dec;50(12):3831-7. doi: 10.1128/JCM.01893-12. Epub 2012 Sep 12.
2
Rapid and effective diagnosis of tuberculosis and rifampicin resistance with Xpert MTB/RIF assay: a meta-analysis.Xpert MTB/RIF 检测技术快速诊断结核分枝杆菌及利福平耐药性：Meta 分析。
J Infect. 2012 Jun;64(6):580-8. doi: 10.1016/j.jinf.2012.02.012. Epub 2012 Feb 27.
3
Contribution of dfrA and inhA mutations to the detection of isoniazid-resistant Mycobacterium tuberculosis isolates.dfrA和inhA基因突变对耐异烟肼结核分枝杆菌分离株检测的贡献。
Antimicrob Agents Chemother. 2009 Sep;53(9):4010-2. doi: 10.1128/AAC.00433-09. Epub 2009 Jul 6.
4
Pyrazinamide resistance among South African multidrug-resistant Mycobacterium tuberculosis isolates.南非耐多药结核分枝杆菌分离株中的吡嗪酰胺耐药性
J Clin Microbiol. 2008 Oct;46(10):3459-64. doi: 10.1128/JCM.00973-08. Epub 2008 Aug 27.
5
Evaluation of the GenoType MTBDRplus assay for rifampin and isoniazid susceptibility testing of Mycobacterium tuberculosis strains and clinical specimens.用于结核分枝杆菌菌株和临床标本利福平及异烟肼药敏试验的GenoType MTBDRplus检测方法的评估
J Clin Microbiol. 2007 Aug;45(8):2635-40. doi: 10.1128/JCM.00521-07. Epub 2007 May 30.
6
Microarray-based pncA genotyping of pyrazinamide-resistant strains of Mycobacterium tuberculosis.基于微阵列的结核分枝杆菌耐吡嗪酰胺菌株的pncA基因分型
J Med Microbiol. 2005 Dec;54(Pt 12):1127-1131. doi: 10.1099/jmm.0.46129-0.
7
High prevalence of KatG Ser315Thr substitution among isoniazid-resistant Mycobacterium tuberculosis clinical isolates from northwestern Russia, 1996 to 2001.1996年至2001年俄罗斯西北部耐异烟肼结核分枝杆菌临床分离株中KatG基因Ser315Thr替换的高流行率
Antimicrob Agents Chemother. 2002 May;46(5):1417-24. doi: 10.1128/AAC.46.5.1417-1424.2002.
8
Characterization of pncA mutations of pyrazinamide-resistant Mycobacterium tuberculosis in Korea.韩国耐吡嗪酰胺结核分枝杆菌pncA基因突变特征分析
J Korean Med Sci. 2001 Oct;16(5):537-43. doi: 10.3346/jkms.2001.16.5.537.
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Evaluation of the BACTEC MGIT 960 and the MB/BacT systems for recovery of mycobacteria from clinical specimens and for species identification by DNA AccuProbe.评估BACTEC MGIT 960和MB/BacT系统从临床标本中分离分枝杆菌以及通过DNA AccuProbe进行菌种鉴定的能力。
J Clin Microbiol. 2000 Jan;38(1):398-401. doi: 10.1128/JCM.38.1.398-401.2000.
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Characterization of new mutations in pyrazinamide-resistant strains of Mycobacterium tuberculosis and identification of conserved regions important for the catalytic activity of the pyrazinamidase PncA.结核分枝杆菌耐吡嗪酰胺菌株新突变的特征分析及对吡嗪酰胺酶PncA催化活性重要的保守区域的鉴定。
Antimicrob Agents Chemother. 1999 Jul;43(7):1761-3. doi: 10.1128/AAC.43.7.1761.
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