Sartori Neimar, Stolf Sheila C, Silva Silvana B, Lopes Guilherme C, Carrilho Marcela
Division of Restorative Science, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.
J Dent. 2013 Dec;41(12):1188-95. doi: 10.1016/j.jdent.2013.09.004. Epub 2013 Sep 25.
The aim of this clinical study was to evaluate the long-term clinical performance of non-carious Class V restorations with and without application of chlorhexidine digluconate to acid-etched dentine.
After the approval of the Ethics and Informed Consent Committee, 70 non-carious cervical lesions were selected and randomly assigned into two groups, according to the split mouth design. The control group was restored with a two-step etch-and-rinse adhesive (Adper Single Bond 2) following manufacturer's instructions; whereas in the experimental group 2% chlorhexidine digluconate solution was applied to acid etched dentine for 30s after etching and prior to the adhesive application. All lesions were restored with a nanofilled composite resin (Filtek Supreme XT) and polymerized with a light-curing unit operating at 600mW/cm(2). Clinical performance was recorded after 1 week, 6, 12, and 36 months using modified Ryge/USPHS criteria in terms of retention, marginal discoloration, marginal integrity, post-operative sensitivity, and secondary caries incidence. Data were analyzed using Chi-Square, Fisher's exact test and McNemar tests (α=.05).
After 36 months the control group showed a success rate of 88% in comparison to 76% of experimental group; however, no statistically difference between them was found (p=.463). Moreover, no statistical differences were observed between groups in the criteria post-operative sensitivity, marginal discoloration, marginal integrity, and secondary caries incidence between the two groups.
The addition of 2% chlorhexidine digluconate conditioning step does not improve the clinical durability of adhesive restorations.
本临床研究旨在评估在酸蚀牙本质上应用或不应用葡萄糖酸氯己定的情况下，非龋性V类洞修复体的长期临床性能。
经伦理和知情同意委员会批准后，根据双侧对照设计，选择70例非龋性颈部病变并随机分为两组。对照组按照制造商说明用两步酸蚀冲洗粘结剂（Adper Single Bond 2）进行修复；而在实验组中，酸蚀后、粘结剂应用前，将2%葡萄糖酸氯己定溶液应用于酸蚀牙本质30秒。所有病变均用纳米填充复合树脂（Filtek Supreme XT）修复，并用功率为600mW/cm(2)的光固化装置进行聚合。使用改良的Ryge/USPHS标准，在1周、6个月、12个月和36个月后记录临床性能，包括固位、边缘变色、边缘完整性、术后敏感性和继发龋发生率。数据采用卡方检验、Fisher精确检验和McNemar检验进行分析（α = 0.05）。
36个月后，对照组成功率为88%，实验组为76%；然而，两组之间未发现统计学差异（p = 0.463）。此外，两组在术后敏感性、边缘变色、边缘完整性和继发龋发生率标准方面也未观察到统计学差异。
添加2%葡萄糖酸氯己定预处理步骤并不能提高粘结修复体的临床耐久性。
