Läuchli S, Bayard I, Hafner J, Hunziker T, Mayer D, French L
Hautarzt. 2013 Dec;64(12):917-22. doi: 10.1007/s00105-013-2671-5.
Leg ulcers are a symptom of a heterogeneous group of diseases. Their treatment causes substantial costs due to the long healing times and extensive wound care measures. There is a paucity of information about healing times and the necessity of hospital treatment for leg ulcers of different etiologies.
In this retrospective study, healing times and the frequency of in-hospital treatment of 355 patients with leg ulcers attending a wound care clinic of a university hospital were examined.
The proportion of healed ulcers was 32.0% after 3 months and 54.3% after 6 months with an average treatment duration of 6.1 months for all ulcers. This proportion of healed ulcers was higher for venous ulcers with 45.5% after 3 months and 63.0% after 6 months, whereas only 30.0% of mixed arterial-venous ulcers and 35.0% of hypertensive ischemic leg ulcers (HYTILU) were healed after 6 months. Of the latter group, 71% of patients were hospitalized at least once during the observation period as compared to 47% of patients with a venous ulcer. The duration of the hospital stay was longer for mixed ulcers and HYTILU with an average of 30 days vs. 23 days for venous ulcers.
These data indicate that the healing times of ulcers of different etiologies differ substantially and that especially ulcers with arteriosclerosis as a causative factor have longer healing times. The fact that they require in-hospital treatment more frequently and for longer periods has significant socio-economic consequences.
腿部溃疡是一组异质性疾病的症状。由于愈合时间长和广泛的伤口护理措施，其治疗成本高昂。关于不同病因的腿部溃疡的愈合时间和住院治疗必要性的信息匮乏。
在这项回顾性研究中，对一家大学医院伤口护理诊所的355例腿部溃疡患者的愈合时间和住院治疗频率进行了检查。
所有溃疡的平均治疗持续时间为6.1个月，3个月后溃疡愈合比例为32.0%，6个月后为54.3%。静脉性溃疡的愈合比例更高，3个月后为45.5%，6个月后为63.0%，而混合动静脉性溃疡和高血压缺血性腿部溃疡（HYTILU）在6个月后仅有30.0%和35.0%愈合。在后一组中，71%的患者在观察期内至少住院一次，而静脉性溃疡患者的这一比例为47%。混合性溃疡和HYTILU的住院时间更长，平均为30天，而静脉性溃疡为23天。
这些数据表明，不同病因的溃疡愈合时间差异很大，尤其是以动脉硬化为致病因素的溃疡愈合时间更长。它们更频繁且更长时间地需要住院治疗这一事实具有重大的社会经济影响。
