de Achaval Sofia, Suarez-Almazor Maria E
Ms Achaval is senior coordinator of clinical trials, and Dr Suarez-Almazor is professor in the department of general internal medicine, ambulatory treatment, and emergency care at the University of Texas M. D. Anderson Cancer Center in Houston. Dr Suarez-Almazor has a K24 career award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases and is director and principal investigator of the Houston CERT, one of the Centers for Education & Research on Therapeutics, a multicenter research program funded by the Agency for Healthcare Research and Quality. She has received honoraria as a speaker from Bristol-Myers Squibb, Roche, and Amgen.
J Musculoskelet Med. 2010 Oct 12;27(10).
Further evaluation of reasons for treatment nonadherence in patients with rheumatologic disease is key in the development of successful interventions. Patient education efforts alone are not sufficient to improve adherence; complex interventions are most effective. Because most rheumatologic diseases require lifetime therapy, the consequences of nonadherence can be deleterious. Several direct and indirect methods have been proposed to measure adherence. Pharmacy claims data have been used frequently in studying rheumatologic disease; electronic monitoring provides an accurate measure. Adherence is mediated through constructs of the patient-physician relationship.
进一步评估风湿性疾病患者治疗不依从的原因是成功干预措施发展的关键。仅靠患者教育努力不足以提高依从性;复杂的干预措施最有效。由于大多数风湿性疾病需要终身治疗,不依从的后果可能是有害的。已经提出了几种直接和间接的方法来衡量依从性。药房报销数据在研究风湿性疾病中经常被使用;电子监测提供了一种准确的测量方法。依从性是通过医患关系的构建来调节的。