Han Lina, Kim Yeong Shik, Cho Seonho, Park Youmie
College of Pharmacy and Natural Products Research Institute, Seoul National University, Seoul 151-742, Republic of Korea.
Nat Prod Commun. 2013 Aug;8(8):1149-52.
We report the use of water extracts of two invertebrates, snail body and earthworm, as biocompatible reducing agents for the green synthesis of gold and silver nanoparticles. The reaction conditions were optimized by varying the extract concentration, gold ion or silver ion concentration, reaction time, and reaction temperature. The gold and silver nanoparticles exhibited their characteristic surface plasmon resonance bands. Mostly spherical and amorphous shapes of the nanoparticles were synthesized. The average diameters of the gold and silver nanoparticles were 4.56 +/- 1.81 nm and 11.12 +/- 5.25 nm, respectively, when the extract of snail body was used as the reducing agent. The earthworm extracts produced gold and silver nanoparticles with average diameters of 6.70 +/- 2.69 nm and 12.19 +/- 4.28 nm, respectively. This report suggests that the invertebrate natural products have potential as biocompatible reducing agents for the green synthesis of metallic nanoparticles. This utility would open up novel applications of invertebrate natural products as nanocomposites and in nanomedicine.
我们报道了使用两种无脊椎动物（蜗牛身体和蚯蚓）的水提取物作为生物相容性还原剂，用于绿色合成金和银纳米颗粒。通过改变提取物浓度、金离子或银离子浓度、反应时间和反应温度来优化反应条件。金和银纳米颗粒呈现出其特征性的表面等离子体共振带。合成的纳米颗粒大多为球形和无定形。当使用蜗牛身体提取物作为还原剂时，金和银纳米颗粒的平均直径分别为4.56±1.81纳米和11.12±5.25纳米。蚯蚓提取物产生的金和银纳米颗粒的平均直径分别为6.70±2.69纳米和12.19±4.28纳米。本报告表明，无脊椎动物天然产物有潜力作为生物相容性还原剂用于金属纳米颗粒的绿色合成。这种用途将开辟无脊椎动物天然产物作为纳米复合材料和用于纳米医学的新应用。
