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以孤立性肺肿块形式出现的结节病。

Sarcoidosis presenting as a solitary pulmonary mass.

作者信息

Mulkareddy Vani, Bhalla Varun, Gurell Michael

机构信息

Department of Internal Medicine, Rochester General Hospital, USA.

Department of Pulmonology and Critical Care, Rochester General Hospital, USA.

出版信息

Respir Med Case Rep. 2020 Oct 12;31:101256. doi: 10.1016/j.rmcr.2020.101256. eCollection 2020.

DOI:10.1016/j.rmcr.2020.101256
PMID:33101899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7569209/
Abstract

Sarcoidosis has a wide varying presentation. Pulmonary sarcoidosis typically presents with bilateral hilar adenopathy and reticulonodular opacities. Very rarely it can present as a single solitary mass. Here we present a case of a 39 year old African-American male who presented with cough and pleuritic chest pain. Initial imaging revealed a right lower lobe airspace opacity, concerning for pneumonia. Despite treatment with antibiotics, symptoms and radiological findings persisted. A PET scan revealed a FDG positive right lower lobe pulmonary mass. Biopsy of the mass and lymph nodes revealed non-caseating granulomas suggestive of sarcoidosis. This case showcases a rare presentation of pulmonary nodular sarcoidosis.

摘要

结节病的表现多种多样。肺结节病通常表现为双侧肺门淋巴结肿大和网状结节状阴影。极少数情况下,它可表现为单个孤立性肿块。在此,我们报告一例39岁非裔美国男性病例,该患者表现为咳嗽和胸膜炎性胸痛。初始影像学检查显示右下叶实变影,怀疑为肺炎。尽管使用了抗生素治疗,但症状和影像学表现持续存在。PET扫描显示右下叶肺部肿块FDG阳性。对该肿块及淋巴结进行活检,结果显示为非干酪样肉芽肿,提示结节病。该病例展示了肺结节病的一种罕见表现形式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d7/7569209/7f75a1a0b208/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d7/7569209/ea44ff2fbed6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d7/7569209/b60a806c6f31/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d7/7569209/7f75a1a0b208/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d7/7569209/ea44ff2fbed6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d7/7569209/b60a806c6f31/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d7/7569209/7f75a1a0b208/gr3.jpg

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本文引用的文献

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Nodular Sarcoidosis Masquerading as Cancer.伪装成癌症的结节病
Clin Med Insights Circ Respir Pulm Med. 2017 Apr 12;11:1179548417703123. doi: 10.1177/1179548417703123. eCollection 2017.
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Case series and literature review of multiple nodular sarcoidosis.多发性结节性结节病的病例系列及文献综述
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