Verma Shyam B
Consultant Dermatologist, Nirvana Skin Clinic, Vadodara, Gujarat, India.
Indian J Dermatol. 2013 Sep;58(5):393-5. doi: 10.4103/0019-5154.117317.
A case of Papular acantholytic dermatosis restricted to the perianal area is being reported in a 26 year old male without involvement of the genitalia, groin and upper thighs for the first time in English literature. The patient presented with long standing grayish white confluent papules with eroded areas in the perianal region which were asymptomatic for a long time before the area got macerated. He did not respond to many weeks of topical steroids but is now showing improvement with topical tacrolimus ointment 0.1% applied twice daily. This entity appears to be very uncommon and also underreported. It is also suggested that this entity be included in the long list of non venereal anogenital lesions as it may mimic perianal warts or molluscum contagiosum.
据英文文献首次报道，一名26岁男性患丘疹性棘层松解性皮肤病，病变仅局限于肛周区域，未累及生殖器、腹股沟及大腿上部。患者肛周长期存在灰白色融合性丘疹及糜烂区域，在该区域浸渍前很长一段时间内无症状。他对数周的外用类固醇治疗无反应，但目前使用0.1%的外用他克莫司软膏，每天涂抹两次，病情正在好转。这种疾病似乎非常罕见，报道也较少。还建议将其列入众多非性传播的肛门生殖器病变之中，因为它可能会模仿肛周疣或传染性软疣。
