Krishnan R S, Ledbetter L S, Reed J A, Hsu S
Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Cutis. 2001 Mar;67(3):217-9, 220.
Acantholytic dermatosis of the vulvocrural area is a rare skin disorder characterized by solitary or multiple skin-colored to white, smooth papules or plaques. Histopathological features of both Hailey-Hailey disease and Darler's disease are present. There is acantholysis, which may involve the full thickness of the epidermis, and dyskeratosis with corps ronds and grains. There may be marked hyperkeratosis and focal parakeratosis. We report a case of this rare disease and discuss its differential diagnosis and treatment.
腹股沟外阴部棘层松解性皮病是一种罕见的皮肤疾病，其特征为单个或多个肤色至白色的光滑丘疹或斑块。同时具备黑利-黑利病和达莱尔病的组织病理学特征。存在棘层松解，可累及表皮全层，以及有圆体细胞和谷粒细胞的角化不良。可能有明显的角化过度和灶性角化不全。我们报告了一例这种罕见疾病，并讨论了其鉴别诊断和治疗方法。
