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外阴丘疹性棘层松解性角化不良症的激光治疗成功:病例报告及文献复习。

Successful laser therapy of a papular acantholytic dyskeratosis of the vulva: case report and review of literature.

机构信息

Department of Obstetrics and Gynecology, University Hospital Schleswig-Holstein, Campus Luebeck, Ratzeburger Allee 160, Luebeck, Germany.

出版信息

Arch Gynecol Obstet. 2010 Apr;281(4):723-5. doi: 10.1007/s00404-009-1313-8. Epub 2009 Dec 15.

Abstract

BACKGROUND

The papular acantholytic dyskeratosis summarizes a collection of papular skin lesions which occur in intertriginous areas and in the genital area. They show a very characteristic histology without the connection to a syndrome such as the Hailey-Hailey disease or the Darier disease.

METHODS

We present the case of an affected 45-year-old woman and evaluate the laser therapy as therapeutic option.

RESULTS

A long lasting reduction of the symptoms was achieved by paying special attention to involving the deep tissue layers while performing the laser therapy. Despite causing a long and painful healing process, this was the only way to achieve a lasting reduction of the symptoms.

CONCLUSIONS

Laser therapy in afflicted areas can improve the symptoms of the papular acantholytic dyskeratosis. The deep tissue laser therapy showed more success than the superficial laser therapy.

摘要

背景

丘疹性棘层松解性角化不良症总结了一组发生在皱褶部位和生殖器区域的丘疹性皮肤损害。它们表现出非常特征性的组织病理学,与 Hailey-Hailey 病或 Darier 病等综合征没有联系。

方法

我们介绍了一位受影响的 45 岁女性患者,并评估了激光治疗作为治疗选择。

结果

通过特别注意在进行激光治疗时涉及深层组织层,我们实现了症状的长期缓解。尽管激光治疗过程漫长且痛苦,但这是实现症状长期缓解的唯一方法。

结论

受累区域的激光治疗可以改善丘疹性棘层松解性角化不良症的症状。深层组织激光治疗比浅层激光治疗效果更好。

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