Diagnostic Center MMM group & Specialist Hospital Yola, Hospital Road, P.M.B. 2266, Yola, Adamawa State, Nigeria.
Asian Pac J Trop Med. 2013 Nov;6(11):865-8. doi: 10.1016/S1995-7645(13)60154-6.
To assess the prevalence of malaria parasitemia in north-east Nigeria and to evaluate the measures for the prevention of malaria.
A village in north-eastern Nigeria was selected for the cross sectional study at the height of the rainy season in October 2011. A total of 550 inhabitants of a hamlet were recruited for this study. After obtaining the consent individuals received a structured interview and were tested for malaria parasites in their blood films. Recruits testing positive for malaria were given a course of artemesinin-based combination therapy (ACT).
A total of 497 inhabitants representing approximately 90 percent of the population participated: a quarter of the study group carried malaria parasitesexclusively Plasmodium falciparum(P. falciparum)-representing a P. falciparum parasite rate (PfPR) of 24.5%. Besides, 53/138 in the age group of 2 to < 10 years old children tested positive for P. falciparum representing a PfPR2-10 value of 38.4%. Malaria control measures were used in just under a third (157/497) of this cohort. Despite these measures 28/157 (17.8%) still tested positive for P. falciparum.
The malaria burden is overestimated for this region in north-east Nigeria. The findings support an intermediate pattern of malaria endemicity. The 30% bed nets coverage for malaria control is well below the WHO estimates for 2011.
评估尼日利亚东北部疟疾寄生虫血症的流行情况，并评估疟疾预防措施。
在 2011 年 10 月雨季高峰期，选择尼日利亚东北部的一个村庄进行横断面研究。共有 550 名小村庄居民被招募参加这项研究。在获得同意后，个体接受了结构访谈，并在其血液涂片上检测疟原虫。检测出疟原虫阳性的招募者给予青蒿素为基础的联合治疗（ACT）。
共有 497 名居民代表了大约 90%的人口参与了研究：研究组中有四分之一的人携带疟疾寄生虫，仅为恶性疟原虫（P. falciparum）-表示恶性疟原虫寄生虫率（PfPR）为 24.5%。此外，53/138 岁的儿童对恶性疟原虫呈阳性，PfPR2-10 值为 38.4%。在这一队列中，只有不到三分之一（157/497）的人使用了疟疾控制措施。尽管采取了这些措施，仍有 28/157（17.8%）人检测出恶性疟原虫阳性。
尼日利亚东北部该地区的疟疾负担被高估。这一发现支持疟疾中度流行的模式。疟疾控制的 30%蚊帐覆盖率远低于世卫组织 2011 年的估计。
