[宋内志贺氏菌O抗原多糖四糖重复连接的理论构象分析]
[Theoretical conformation analysis of tetrasaccharide-repeated links of the Shigella flexneri O-antigenic polysaccharide].
作者信息
Lipkind G M, Kochetkov N K
出版信息
Bioorg Khim. 1985 Apr;11(4):539-49.
PMID:2408628
Abstract
Theoretical conformational analysis of four tetrasaccharide repeating units of the Shigella flexneri serogroup Y polysaccharide has been carried out. Interdependency of conformational states of neighbouring disaccharide units in the oligosaccharides has been investigated and conformational distribution of tetrasaccharides in solution calculated. Taking into account the entropy of oligosaccharide chains is shown to lead to significant correction of the results.
摘要
对福氏志贺菌Y群多糖的四个四糖重复单元进行了理论构象分析。研究了寡糖中相邻二糖单元构象状态的相互依赖性，并计算了溶液中四糖的构象分布。结果表明，考虑寡糖链的熵会导致结果的显著校正。
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