Huaxi MR Research Center, Sichuan University, Chengdu, Sichuan 610065, China; College of Computer Science, Sichuan University, Chengdu, Sichuan 610065, China; and Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, Tennessee 37232-2310.
Med Phys. 2013 Oct;40(10):101904. doi: 10.1118/1.4820370.
Noise in magnetic resonance imaging (MRI) data is widely recognized to be harmful to image processing and subsequent quantitative analysis. To ameliorate the effects of image noise, the authors present a structure-tensor based nonlocal mean (NLM) denoising technique that can effectively reduce noise in MRI data and improve tissue characterization.
The proposed 3D NLM algorithm uses a structure tensor to characterize information around tissue boundaries. The similarity weight of a pixel (or patch), which determines its contribution to the denoising process, is determined by the intensity and structure tensor simultaneously. Meanwhile, similarity of structure tensors is computed using an affine-invariant Riemannian metrics, which compares tensor properties more comprehensively and avoids orientation inaccuracy of structure subsequently. The proposed method is further extended for denoising high dimensional MRI data such as diffusion weighted MRI. It is also extended to handle Rician noise corruption so that denoising effects are further enhanced.
The proposed method was implemented in both simulated datasets and multiply modalities of real 3D MRI datasets. Comparisons with related state-of-the-art algorithms demonstrated that this method improves denoising performance qualitatively and quantitatively.
In this paper, high order structure information of 3D MRI was characterized by 3D structure tensor and compared for NLM denoising in a Riemannian space. Experiments with simulated and real human MRI data demonstrate a great potential of the proposed technique for routine clinical use.
磁共振成像(MRI)数据中的噪声被广泛认为对图像处理和后续的定量分析有害。为了减轻图像噪声的影响,作者提出了一种基于结构张量的非局部均值(NLM)去噪技术,该技术可以有效地降低 MRI 数据中的噪声并提高组织特征描述能力。
所提出的 3D NLM 算法使用结构张量来描述组织边界周围的信息。像素(或补丁)的相似性权重决定了其对去噪过程的贡献,该权重由强度和结构张量同时确定。同时,使用仿射不变黎曼度量来计算结构张量的相似性,这可以更全面地比较张量属性,避免结构的方向不准确。该方法进一步扩展到去噪高维 MRI 数据,如扩散加权 MRI。它还扩展到处理瑞利噪声污染,从而进一步增强去噪效果。
该方法在模拟数据集和多种真实 3D MRI 数据集上进行了实现。与相关的最先进算法的比较表明,该方法在定性和定量上都提高了去噪性能。
在本文中,通过 3D 结构张量对 3D MRI 的高阶结构信息进行了特征描述,并在黎曼空间中进行了 NLM 去噪比较。对模拟和真实人体 MRI 数据的实验表明,该技术在常规临床应用中有很大的潜力。