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通过疫苗接种在德国根除蓝舌病

Eradication of bluetongue disease in Germany by vaccination.

作者信息

Baetza Hans-Joachim

机构信息

Federal Ministry of Food, Agriculture and Consumer Protection, Rochusstrasse 1, 53123 Bonn, Germany.

出版信息

Vet Immunol Immunopathol. 2014 Mar 15;158(1-2):116-9. doi: 10.1016/j.vetimm.2013.09.001. Epub 2013 Sep 7.

DOI:10.1016/j.vetimm.2013.09.001
PMID:24090604
Abstract

Bluetongue disease first broke out in Germany on 21 August 2006, almost simultaneously with the first outbreaks in Belgium and The Netherlands. More extensive tests showed that the serotype was serotype 8. Due to westerly winds the disease spread rapidly towards the East, with the result that in the year 2008 large parts of Germany were affected. The traditional methods of animal disease control were not of much help in view of the transmission of the disease by insects; the speed of the spread of the disease could only be slowed down by movement restrictions, but could not be influenced in a decisive manner. Authorised vaccines were not (yet) available. A large-scale field study based on three prototypes in bovine animals and sheep revealed that they were both effective and safe. Consequently, the Federal Ministry of Food, Agriculture and Consumer Protection issued an exceptional permission to administer these non-authorised vaccines. In May 2008, large-scale vaccination campaigns were launched (vaccination of all bovines, sheep and goats). As a consequence, the disease outbreak figures declined drastically. In 2009, the last blanket vaccinations were administered and from 2010 animal keepers were allowed to continue vaccinating their livestock on a voluntary basis. Intensive tests (serological, PCR) showed in the years 2010 and 2011 that BTV8 no longer circulated among the livestock population. Effective from 15.02.2012, Germany declared itself free from BTV8 in line with Article 8.3.3 of the OIE Animal Health Code.

摘要

蓝舌病于2006年8月21日在德国首次爆发,几乎与比利时和荷兰的首次疫情同时发生。更广泛的检测表明,血清型为8型。由于西风,该病迅速向东传播,结果在2008年德国大片地区受到影响。鉴于该病通过昆虫传播,传统的动物疾病控制方法帮助不大;疾病传播速度只能通过行动限制来减缓,但无法得到决定性的控制。当时(尚未)有获批的疫苗。一项基于三种牛和羊用疫苗原型的大规模田间研究表明,这些疫苗既有效又安全。因此,联邦食品、农业和消费者保护部发布了一项特殊许可,允许使用这些未经批准的疫苗。2008年5月,开展了大规模疫苗接种运动(对所有牛、羊和山羊进行接种)。结果,疾病爆发数量大幅下降。2009年,进行了最后一轮全面接种,从2010年起,允许动物饲养者自愿继续为其牲畜接种疫苗。2010年和2011年的深入检测(血清学、聚合酶链式反应)表明,BTV8不再在牲畜群体中传播。自2012年2月15日起,德国根据《国际兽疫局动物卫生法典》第8.3.3条宣布本国无BTV8。

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Eradication of bluetongue disease in Germany by vaccination.通过疫苗接种在德国根除蓝舌病
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Control of bluetongue in Europe.欧洲蓝舌病的控制。
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Bluetongue in Denmark during 2008.2008 年丹麦的蓝舌病。
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Tijdschr Diergeneeskd. 2008 Oct 15;133(20):856-8.

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