Fasano Alfonso, Bloem Bastiaan R
Continuum (Minneap Minn). 2013 Oct;19(5 Movement Disorders):1344-82. doi: 10.1212/01.CON.0000436159.33447.69.
This article provides insight and reviews useful tools for the clinical assessment, understanding, and management of neurologic gait disorders.
In recent years, our understanding of the physiology of human walking has steadily increased. The recognition of gait as a complex, "higher-order" form of motor behavior with prominent influence of mental processes has been an important new insight, and the clinical implications of gait disorders are increasingly being recognized. Better classification schemes, the redefinition of established entities (eg, senile gait), and new insights from research on degenerative disorders primarily affecting gait (eg, primary progressive freezing of gait) have become available.
Gait disorders are directly correlated with poor quality of life and increased mortality. Because gait is very sensitive to any insult to the nervous system, its assessment should be carried out carefully in routine clinical practice. Disorders of locomotion are easily discernible to the naked eye. However, when examining gait, clinicians should bear in mind that the clinical phenotype is the net result of changes induced by the disease itself plus any compensations adopted by the patient to improve stability. This review presents a clinically oriented approach to gait disorders based on the dominant phenomenology and underlying pathophysiology, which are tightly connected. The authors conclude by proposing a practical management approach.
本文为神经步态障碍的临床评估、理解及管理提供见解并回顾实用工具。
近年来,我们对人类行走生理学的理解稳步提升。认识到步态是一种复杂的“高阶”运动行为形式,受心理过程显著影响,这是一项重要的新见解,且步态障碍的临床意义日益受到认可。更好的分类方案、既定实体(如老年步态)的重新定义以及主要影响步态的退行性疾病研究(如原发性进行性步态冻结)的新见解已出现。
步态障碍与生活质量差和死亡率增加直接相关。由于步态对神经系统的任何损伤都非常敏感,在常规临床实践中应仔细进行评估。运动障碍肉眼很容易辨别。然而,在检查步态时,临床医生应记住,临床表型是疾病本身引起的变化加上患者为提高稳定性所采取的任何补偿措施的最终结果。本综述基于紧密相关的主要现象学和潜在病理生理学,提出了一种以临床为导向的步态障碍处理方法。作者最后提出了一种实用的管理方法。