临床试验环境下 HIV 感染状况的保密问题：抗逆转录病毒药物筛查有助于区分新发和既往 HIV 感染。
Nondisclosure of HIV status in a clinical trial setting: antiretroviral drug screening can help distinguish between newly diagnosed and previously diagnosed HIV infection.
机构信息
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
出版信息
Clin Infect Dis. 2014 Jan;58(1):117-20. doi: 10.1093/cid/cit672. Epub 2013 Oct 2.
Abstract
In The HIV Prevention Trials Network 061 study, 155 human immunodeficiency virus (HIV)-infected men reported no prior HIV diagnosis; 83 of those men had HIV RNA levels of <1000 copies/mL at enrollment. Antiretroviral drug testing revealed that 65 of the 83 (78.3%) men were on antiretroviral treatment. Antiretroviral drug testing can help distinguish between newly diagnosed and previously diagnosed HIV infection.
摘要
在 HIV 预防试验网络 061 研究中，155 名感染人类免疫缺陷病毒 (HIV) 的男性报告没有 HIV 诊断史；其中 83 名男性在入组时 HIV RNA 水平 <1000 拷贝/mL。抗逆转录病毒药物检测显示，83 名男性中有 65 名（78.3%）正在接受抗逆转录病毒治疗。抗逆转录病毒药物检测有助于区分新发和既往 HIV 感染。
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