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慢性肾脏病的流行情况及其与波兰老年人群社会经济状况的关系:来自全国基于人群的 PolSenior 研究的结果。

The prevalence of chronic kidney disease and its relation to socioeconomic conditions in an elderly Polish population: results from the national population-based study PolSenior.

机构信息

Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia in Katowice, Katowice, Poland.

出版信息

Nephrol Dial Transplant. 2014 May;29(5):1073-82. doi: 10.1093/ndt/gft351. Epub 2013 Oct 3.

Abstract

BACKGROUND

Rapidly progressing ageing of worldwide populations is likely to increase the occurrence of chronic kidney disease (CKD) in the next decades. However, until now little is known about the prevalence of CKD in the Polish elderly population. The aim of this study was to assess the prevalence of CKD and its relation to socioeconomic conditions in the Polish elderly population.

METHODS

A glomerular filtration rate estimated (eGFR) according to the CKD-EPI formula and urine albumin/creatinine ratio were determined in 3797 out of 4979 randomly selected elderly subjects from the national survey study PolSenior. Additionally, some socioeconomic factors related to the prevalence of CKD were also analysed.

RESULTS

The prevalence of CKD in the Polish elderly population was 29.4%. Only 3.2% of elderly subjects with CKD were aware of the disease. CKD was more frequent among urban dwellers, non-smokers, alcohol abstinents and those with low physical activity. Decreased eGFR was more frequent among less educated women, better educated men, blue collar female workers and white collar male workers. Increased albuminuria was associated with low physical activity.

CONCLUSIONS

(i) CKD affects almost one-third of the elderly Polish population. (ii) In Poland elderly subjects with CKD are usually unaware of their kidney disease. (iii) In Polish elderly population, CKD is more frequently present among urban residents, non-smokers, abstainers and less physically active people. (iv) Only in women is higher educational status related to the lower risk of CKD.

摘要

背景

全球人口老龄化的迅速发展,可能会在未来几十年增加慢性肾脏病(CKD)的发生。然而,到目前为止,我们对波兰老年人群中 CKD 的患病率知之甚少。本研究旨在评估 CKD 在波兰老年人群中的患病率及其与社会经济状况的关系。

方法

我们从全国性调查研究 PolSenior 中随机选择了 4979 名老年人中的 3797 名,根据 CKD-EPI 公式估算肾小球滤过率(eGFR)和尿白蛋白/肌酐比值,并分析了一些与 CKD 患病率相关的社会经济因素。

结果

波兰老年人群中 CKD 的患病率为 29.4%。只有 3.2%的 CKD 患者知晓自己患有该病。CKD 在城市居民、不吸烟者、不饮酒者和体力活动较少者中更为常见。eGFR 降低在受教育程度较低的女性、受教育程度较高的男性、蓝领女性工人和白领男性工人中更为常见。白蛋白尿增加与体力活动减少有关。

结论

(i)CKD 影响了近三分之一的波兰老年人口。(ii)在波兰,老年 CKD 患者通常不知道自己患有肾脏疾病。(iii)在波兰老年人群中,CKD 更常见于城市居民、不吸烟者、不饮酒者和体力活动较少者。(iv)只有女性的受教育程度与 CKD 风险降低有关。

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