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上肢神经鞘瘤。

Schwannoma in the upper limbs.

机构信息

Department of Orthopaedics & Traumatology, University of Hong Kong, 5/F, Professorial Block, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong.

出版信息

Biomed Res Int. 2013;2013:167196. doi: 10.1155/2013/167196. Epub 2013 Sep 4.

Abstract

Schwannomas are the commonest tumours of peripheral nerves. Despite the classical description that schwannomas are well encapsulated and can be completely enucleated during excision, a portion of them have fascicular involvement and could not be completely shelled out. A retrospective review for 8 patients was carried out over 10 years. 75% of schwannoma occurred over the distal region of upper limb (at elbow or distal to it). It occurs more in the mixed nerve instead of pure sensory or motor nerve. 50% of patients had mixed nerve involvement. Fascicular involvement was very common in schwannoma (75% of patients). Removal of the tumour with fascicles can cause functional deficit. At present, there is no method (including preoperative MRI) which can predict the occurrence of fascicular involvement; the authors therefore proposed a new system to stratify patients who may benefit from interfascicular nerve grafts. In this group of patients, the authors strongly recommend that the possibility and option of nerve graft should be discussed with patients prior to schwannoma excision, so that nerve grafting could be directly proceeded with patient consent in case there is fascicular involvement of tumour found intraoperatively.

摘要

神经鞘瘤是周围神经最常见的肿瘤。尽管经典描述神经鞘瘤包膜完整,可以在切除时完全切除,但其中一部分有束状累及,不能完全切除。对 10 年内的 8 例患者进行了回顾性研究。75%的神经鞘瘤发生在上肢远端(肘部或其远端)。它更多发生在混合神经而不是单纯的感觉或运动神经。50%的患者有混合神经受累。束状累及在神经鞘瘤中非常常见(75%的患者)。切除带有束的肿瘤可能会导致功能缺损。目前,没有任何方法(包括术前 MRI)可以预测束状累及的发生;因此,作者提出了一种新的系统来对可能受益于束间神经移植的患者进行分层。在这组患者中,作者强烈建议在切除神经鞘瘤前与患者讨论神经移植的可能性和选择,以便在术中发现肿瘤束状累及时,在获得患者同意的情况下直接进行神经移植。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5489/3777180/b7997de51dcd/BMRI2013-167196.001.jpg

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