Department of Orthopedics, National Cheng Kung University Hospital, Tainan, Taiwan.
College of Medicine, National Cheng Kung University, Tainan, Taiwan.
BMC Surg. 2024 Oct 3;24(1):284. doi: 10.1186/s12893-024-02583-0.
Schwannomas are benign, slow-growing tumors originating from Schwann cells in peripheral nerves, commonly affecting the median and ulnar nerves in the forearm and wrist. Surgical excision is the gold standard treatment. This study presents our treatment strategies and outcomes for large-sized ulnar and median nerve schwannomas at the forearm and wrist level.
From 2012 to 2023, we enrolled 15 patients with schwannomas over 2 cm in size in the median or ulnar nerve at the forearm and wrist. The study included 12 patients with median nerve schwannomas (mean age: 61 years) and 3 with ulnar nerve schwannomas (mean age: 68 years), with a mean follow-up of 26.9 months.
After surgery, all patients with median nerve schwannomas experienced mild, transient numbness affecting fewer than two digits, resolving within six months without motor deficits. Ulnar nerve schwannoma excision caused mild numbness in two patients, also resolving within six months, but all three developed ulnar claw hand deformity, which persisted but improved at the last follow-up. Despite this, patients were satisfied with the surgery due to relief from severe tingling pain.
Schwannomas of the median, ulnar, and other peripheral nerves should be removed by carefully dissecting the connecting nerve fascicles to avoid injury to healthy ones. Sensory deficits may occur but are unlikely to significantly impact quality of life. However, in motor-dominant nerves like the ulnar nerve, there is a risk of significant motor deficits that could affect hand function, though not completely. Therefore, thorough preoperative discussion and consideration of interfascicular nerve grafting are essential.
神经鞘瘤是一种起源于周围神经施万细胞的良性、生长缓慢的肿瘤,常见于前臂和腕部的正中神经和尺神经。手术切除是金标准治疗方法。本研究介绍了我们在前臂和腕部对大型正中神经和尺神经神经鞘瘤的治疗策略和结果。
2012 年至 2023 年,我们纳入了 15 例前臂和腕部正中神经或尺神经上直径超过 2cm 的神经鞘瘤患者。研究包括 12 例正中神经神经鞘瘤患者(平均年龄:61 岁)和 3 例尺神经神经鞘瘤患者(平均年龄:68 岁),平均随访 26.9 个月。
手术后,所有正中神经神经鞘瘤患者均出现短暂性轻度、影响不到两个手指的麻木感,在 6 个月内缓解,无运动功能障碍。尺神经鞘瘤切除导致 2 例患者出现轻度麻木,也在 6 个月内缓解,但 3 例患者均出现尺神经爪形手畸形,最后随访时仍存在,但有所改善。尽管如此,由于严重刺痛感得到缓解,患者对手术感到满意。
正中神经、尺神经和其他周围神经的神经鞘瘤应通过仔细解剖连接神经束来切除,以避免损伤健康神经。可能会出现感觉缺失,但不太可能显著影响生活质量。然而,在像尺神经这样以运动为主的神经中,存在显著运动功能障碍的风险,可能会影响手部功能,但并非完全如此。因此,彻底的术前讨论和考虑神经束间移植是必要的。