Austrian Cluster for Tissue Regeneration and Ludwig Boltzmann Institute for Experimental and Clinical Traumatology at the Research Centre for Trauma of the Austrian Workers' Compensation Board (AUVA), Vienna, Austria; Department for Trauma Surgery and Sports Traumatology, Paracelsus Medical University, Salzburg, Austria; Department for Surgery, State Hospital Hainburg, Hainburg, Austria.
Int Rev Neurobiol. 2013;109:85-98. doi: 10.1016/B978-0-12-420045-6.00003-1.
Low-energy extracorporeal shock wave treatment (ESWT) is a relatively new therapeutic tool that is widely used for the treatment of epicondylitis and plantar fasciitis and to foster bone and wound healing. Shock waves, sonic pulses with high energy impact, are thought to induce biochemical changes within the targeted tissues through mechanotransduction. The biological effects of ESWT are manifested in improved vascularization, the local release of growth factors, and local anti-inflammatory effects, but the target cells too are influenced. ESWT appears to have differential effects on peripheral nerves and has been proved to promote axonal regeneration after axotomy. This review discusses the effects of ESWT on intact and injured peripheral nerves and suggests a multiple mechanism of action.
低能量体外冲击波治疗（ESWT）是一种相对较新的治疗工具，广泛用于治疗网球肘和足底筋膜炎，并促进骨骼和伤口愈合。冲击波是具有高能量冲击的声波脉冲，被认为通过机械转导在靶向组织内引起生化变化。ESWT 的生物学效应表现为改善血管生成、局部生长因子释放和局部抗炎作用，但也影响靶细胞。ESWT 似乎对周围神经有不同的影响，并已被证明可促进轴突切断后的轴突再生。这篇综述讨论了 ESWT 对完整和受损周围神经的影响，并提出了多种作用机制。
