Institute of Digestive Diseases and State Key Laboratory of Digestive Diseases, Department of Medicine & Therapeutics, LKS Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Semin Cancer Biol. 2013 Dec;23(6 Pt B):469-70. doi: 10.1016/j.semcancer.2013.09.006. Epub 2013 Oct 3.
Digestive cancers, such as colorectal cancer, gastric cancer and liver cancer, remain major threats to human health in coming decades and their epidemiology is under dynamic changes. Recent advances in genotyping and sequencing technologies together with other molecular and cellular biology techniques have led to a clearer delineation of the pathogenic mechanisms underlying genetic and environmental factors that contribute to digestive cancers. Such expansion of knowledge continues to fuel the development of novel biomarkers and therapeutics. In this special issue of Seminars in Cancer Biology, hot topics in basic and translational research of digestive cancers will be reviewed.
消化系统癌症，如结直肠癌、胃癌和肝癌，在未来几十年仍将是人类健康的主要威胁，其流行病学也在不断变化。基因分型和测序技术的最新进展以及其他分子和细胞生物学技术，使得对遗传和环境因素导致消化系统癌症的发病机制有了更清晰的认识。这些知识的扩展不断推动新的生物标志物和治疗方法的发展。本期《癌症生物学研讨会》特刊将对消化系统癌症基础和转化研究的热门课题进行综述。
