Suppression of human alpha-foetoprotein-producing hepatocellular carcinoma growth in nude mice by an anti alpha-foetoprotein antibody-daunorubicin conjugate with a poly-L-glutamic acid derivative as intermediate drug carrier.
作者信息
Tsukada Y, Ohkawa K, Hibi N
出版信息
Br J Cancer. 1985 Jul;52(1):111-6. doi: 10.1038/bjc.1985.157.
Abstract
摘要
相似文献
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Suppression of human alpha-foetoprotein-producing hepatocellular carcinoma growth in nude mice by an anti alpha-foetoprotein antibody-daunorubicin conjugate with a poly-L-glutamic acid derivative as intermediate drug carrier.以聚-L-谷氨酸衍生物作为中间药物载体的抗甲胎蛋白抗体-柔红霉素缀合物对裸鼠人甲胎蛋白产生性肝细胞癌生长的抑制作用
Br J Cancer. 1985 Jul;52(1):111-6. doi: 10.1038/bjc.1985.157.
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Effect of a conjugate of daunomycin and antibodies to rat alpha-fetoprotein on the growth of alpha-fetoprotein-producing tumor cells.柔红霉素与大鼠甲胎蛋白抗体的偶联物对产生甲胎蛋白的肿瘤细胞生长的影响。
Proc Natl Acad Sci U S A. 1982 Jan;79(2):621-5. doi: 10.1073/pnas.79.2.621.
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Growth characteristics of alpha-foetoprotein-secreting human hepatocellular carcinoma in athymic (nude) mice.分泌甲胎蛋白的人肝细胞癌在无胸腺（裸）小鼠体内的生长特性
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Immunotoxins composed of monoclonal antibody to alpha-fetoprotein and gelonin as a potent hepatoma-targeted drug delivery system.由抗甲胎蛋白单克隆抗体和去糖链植物凝血素组成的免疫毒素作为一种有效的肝癌靶向给药系统。
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Chemotherapy by intravenous administration of conjugates of daunomycin with monoclonal and conventional anti-rat alpha-fetoprotein antibodies.通过静脉注射柔红霉素与单克隆及传统抗大鼠甲胎蛋白抗体的偶联物进行化疗。
Proc Natl Acad Sci U S A. 1982 Dec;79(24):7896-9. doi: 10.1073/pnas.79.24.7896.
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Coupling daunorubicin to monoclonal antialphafoetoprotein with a new activated derivative.用一种新型活化衍生物将柔红霉素与单克隆抗甲胎蛋白偶联。
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A novel method of conjugation of daunomycin with antibody with a poly-L-glutamic acid derivative as intermediate drug carrier. An anti-alpha-fetoprotein antibody-daunomycin conjugate.一种以聚-L-谷氨酸衍生物作为中间药物载体将柔红霉素与抗体偶联的新方法。一种抗甲胎蛋白抗体-柔红霉素偶联物。
J Med Chem. 1984 Dec;27(12):1602-7. doi: 10.1021/jm00378a013.
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The effects of co-administration of selenium and cis-platin (CDDP) on CDDP-induced toxicity and antitumour activity.硒与顺铂（CDDP）联合给药对顺铂诱导的毒性和抗肿瘤活性的影响。
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Selective in vitro and in vivo growth inhibition against human yolk sac tumor cell lines by purified antibody against human alpha-fetoprotein conjugated with mitomycin C via human serum albumin.通过人血清白蛋白与丝裂霉素C偶联的抗人甲胎蛋白纯化抗体对人卵黄囊瘤细胞系进行体外和体内选择性生长抑制。
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Evaluation of a conjugate of purified antibodies against human AFP-dextran-daunorubicin to human AFP-producing yolk sac tumor cell lines.针对人甲胎蛋白（AFP）产生的卵黄囊肿瘤细胞系，对纯化的抗人AFP-葡聚糖-柔红霉素抗体偶联物进行评估。
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本文引用的文献
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Antitumour reactions of monoclonal antibody against a human osteogenic-sarcoma cell line.抗人骨肉瘤细胞系单克隆抗体的抗肿瘤反应
Br J Cancer. 1981 May;43(5):582-7. doi: 10.1038/bjc.1981.87.
2
Evaluation of drug-antibody conjugates in the treatment of human myelosarcomas transplanted in nude mice.评估药物-抗体偶联物在治疗裸鼠移植人骨髓肉瘤中的作用。
Cancer. 1980 Mar 15;45(6):1326-33. doi: 10.1002/1097-0142(19800315)45:6<1326::aid-cncr2820450610>3.0.co;2-y.
3
Preparation and properties of a drug-carrier-antibody conjugate showing selective antibody-directed cytotoxicity in vitro.一种在体外显示出选择性抗体导向细胞毒性的药物-载体-抗体偶联物的制备及其性质
Int J Cancer. 1983 May 15;31(5):661-70. doi: 10.1002/ijc.2910310520.
4
Selective cytotoxicity against human tumour cells by a vindesine-monoclonal antibody conjugate.长春地辛-单克隆抗体偶联物对人肿瘤细胞的选择性细胞毒性。
Br J Cancer. 1983 Jan;47(1):43-9. doi: 10.1038/bjc.1983.5.
5
6
Enhanced antitumor activity of mitomycin C conjugated with anti-alpha-fetoprotein antibody by a novel method of conjugation.通过一种新型偶联方法将丝裂霉素C与抗甲胎蛋白抗体偶联，增强其抗肿瘤活性。
J Appl Biochem. 1983 Aug-Oct;5(4-5):313-9.
7
8
The inhibitory effects of horse anti-rat AFP antiserum on the uptake of 2-deoxy-D-glucose by AFP-producing rat hepatoma cells.马抗大鼠甲胎蛋白抗血清对产生甲胎蛋白的大鼠肝癌细胞摄取2-脱氧-D-葡萄糖的抑制作用。
Int J Cancer. 1984 Apr 15;33(4):497-502. doi: 10.1002/ijc.2910330413.
9
Effect of a conjugate of daunomycin and purified polyclonal or monoclonal antibodies to rat alpha-fetoprotein on the growth of alpha-fetoprotein-producing tumor cells.柔红霉素与纯化的抗大鼠甲胎蛋白多克隆或单克隆抗体的偶联物对产生甲胎蛋白的肿瘤细胞生长的影响。
Ann N Y Acad Sci. 1983;417:262-9. doi: 10.1111/j.1749-6632.1983.tb32869.x.
10
Chemotherapy by intravenous administration of conjugates of daunomycin with monoclonal and conventional anti-rat alpha-fetoprotein antibodies.通过静脉注射柔红霉素与单克隆及传统抗大鼠甲胎蛋白抗体的偶联物进行化疗。
Proc Natl Acad Sci U S A. 1982 Dec;79(24):7896-9. doi: 10.1073/pnas.79.24.7896.
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