Gunderson Erica P
Cardiovascular Disease and Metabolism Section, Division of Research, Kaiser Permanente Northern California, Oakland, California.
Clin Obstet Gynecol. 2013 Dec;56(4):844-52. doi: 10.1097/GRF.0b013e3182a8e067.
Lactating women exhibit more favorable blood glucose and insulin profiles, as well as increased insulin sensitivity than nonlactating women. Yet, much less is known about whether these favorable effects on metabolic risk factors persist long-term among women with gestational diabetes mellitus (GDM). The evidence that lactation reduces incident type 2 diabetes after GDM pregnancy is limited and inconsistent. Well-controlled, prospective studies that measure lactation intensity and duration, and comprehensively screen for postpartum glucose tolerance are needed to conclusively determine whether lactation can lead to reduced risk of type 2 diabetes after GDM pregnancy.
与非哺乳期女性相比，哺乳期女性的血糖和胰岛素水平更有利，胰岛素敏感性也更高。然而，对于患有妊娠期糖尿病（GDM）的女性，这些对代谢危险因素的有利影响是否能长期持续，人们了解得还很少。关于哺乳期降低GDM妊娠后2型糖尿病发病率的证据有限且不一致。需要进行严格控制的前瞻性研究，测量哺乳强度和持续时间，并全面筛查产后糖耐量，以最终确定哺乳期是否能降低GDM妊娠后2型糖尿病的风险。
