Bunpapong Napawan, Nonthabenjawan Nutthawan, Chaiwong Supassama, Tangwangvivat Ratanaporn, Boonyapisitsopa Supanat, Jairak Waleemas, Tuanudom Ranida, Prakairungnamthip Duangduean, Suradhat Sanipa, Thanawongnuwech Roongroje, Amonsin Alongkorn
Center of Excellence for Emerging and Re-emerging Infectious Diseases in Animals, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Virus Genes. 2014 Feb;48(1):56-63. doi: 10.1007/s11262-013-0978-z. Epub 2013 Oct 8.
In January 2012, several clinical cases of dogs with flu-like symptoms, including coughing, sneezing, nasal discharge, and fever, were reported in a small-animal hospital located in Bangkok, Thailand. One influenza A virus was identified and characterized as an avian-like influenza virus H3N2. The virus was named A/canine/Thailand/CU-DC5299/12. A phylogenetic analysis indicated that the canine virus belonged to an avian Eurasian lineage and was genetically related to the canine influenza viruses H3N2 from China and Korea. This canine virus displays a unique genetic signature with two amino acid insertions in the NA protein, which is similar to the canine influenza viruses from eastern China (Zhejiang and Jiangsu). This study constitutes the first report of H3N2 canine influenza virus infection in a small-animal hospital in Thailand.
2012年1月，泰国曼谷一家小动物医院报告了几例出现流感样症状（包括咳嗽、打喷嚏、流鼻涕和发烧）的犬类临床病例。鉴定出一种甲型流感病毒，并将其特征描述为禽源样H3N2流感病毒。该病毒被命名为A/犬/泰国/CU-DC5299/12。系统发育分析表明，该犬类病毒属于禽源欧亚谱系，与来自中国和韩国的H3N2犬流感病毒存在基因关联。这种犬类病毒在NA蛋白中有两个氨基酸插入，显示出独特的基因特征，这与中国东部（浙江和江苏）的犬流感病毒相似。本研究是泰国一家小动物医院H3N2犬流感病毒感染的首次报告。
