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美国孕妇用药特点:阿片类药物和非阿片类非法药物使用情况。

Characteristics of drug use among pregnant women in the United States: Opioid and non-opioid illegal drug use.

机构信息

Friends Research Institute, Inc., San Francisco, CA, USA.

Columbia University, Mailman School of Public Health, Department of Epidemiology, New York, NY, USA; TrendologyIT Corporation, Baltimore, MD, USA.

出版信息

Drug Alcohol Depend. 2018 Feb 1;183:261-266. doi: 10.1016/j.drugalcdep.2017.11.010. Epub 2017 Dec 27.

Abstract

BACKGROUND

The opioid epidemic in the US is affecting pregnant women and their offspring, with rising numbers of maternal and neonatal treatment episodes. The aim of this study was to characterize pregnant drug users in order to inform intervention strategies based on sociodemographic, mental health, and substance use characteristics.

METHODS

Data on pregnant women aged 18-44 reporting past-year, nonmedical opioid use or use of non-opioid illegal drugs (other than marijuana) were analyzed from the National Survey on Drug Use and Health (2005-2014). Women (N = 818) were categorized into 3 groups: 1) use of opioids only (n = 281), 2) opioid-polydrug users (n = 241), and 3) other (non-opioid) illegal drug users (n = 296). Characteristics between the 3 groups of women were compared using bivariable analyses.

RESULTS

Most women were non-Hispanic White (67.6%), had a high school diploma or less education (61.0%), a household income <$20,000/year (72.2%), and health insurance coverage (84.3%). No significant differences between the three groups were found regarding sociodemographic characteristics. Past-30-day marijuana use was less prevalent among opioid-only users (10.9%) compared to opioid-polydrug users (43.6%) and other pregnant illegal drug users (27.6%) (P < 0.001) and past-year drug/alcohol treatment was less prevalent among opioid-only users (6.3%) compared to opioid-polydrug users (20.3%) and other illegal drug users (8.3%) (P = 0.002). Opioid-only users also reported lower prevalence of past-year depression (P < 0.001) and anxiety (P = 0.039).

CONCLUSIONS

Pregnant drug-using women were often of low socioeconomic status, with mental health and substance use patterns suggesting the need for targeted mental health/substance use screening and interventions before and during pregnancy, particularly for opioid-polydrug users.

摘要

背景

美国的阿片类药物泛滥问题正在影响孕妇及其后代,产妇和新生儿治疗的案例数量不断增加。本研究旨在对孕妇吸毒者进行特征描述,以便根据社会人口统计学、心理健康和物质使用特征制定干预策略。

方法

对《2005-2014 年全国毒品使用与健康调查》中报告过去一年非医疗性阿片类药物使用或使用非阿片类非法药物(不包括大麻)的 18-44 岁孕妇的数据进行了分析。将女性(N=818)分为 3 组:1)仅使用阿片类药物(n=281);2)阿片类药物多药使用者(n=241);3)其他(非阿片类)非法药物使用者(n=296)。使用双变量分析比较 3 组女性之间的特征。

结果

大多数女性是非西班牙裔白人(67.6%),高中及以下学历(61.0%),家庭收入<20000 美元/年(72.2%),有医疗保险(84.3%)。三组女性在社会人口统计学特征方面无显著差异。与阿片类药物多药使用者(43.6%)和其他孕妇非法药物使用者(27.6%)相比,仅使用阿片类药物的女性(10.9%)过去 30 天使用大麻的比例较低(P<0.001),过去一年药物/酒精治疗的比例也较低(6.3%),而阿片类药物多药使用者(20.3%)和其他孕妇非法药物使用者(8.3%)(P=0.002)。仅使用阿片类药物的女性也报告过去一年抑郁症(P<0.001)和焦虑症(P=0.039)的发病率较低。

结论

孕妇吸毒者通常社会经济地位较低,心理健康和物质使用模式表明需要在怀孕前和怀孕期间进行有针对性的心理健康/物质使用筛查和干预,特别是对阿片类药物多药使用者。

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