Norpoth K, Jacob J, Grimmer G, Mohtashamipur E
Zentralbl Bakteriol Mikrobiol Hyg B. 1985 May;180(5-6):540-7.
Automobile exhaust condensate of a passenger car (gasoline engine) was separated into fractions of 2-3 rings containing -, 4-7 rings containing polycyclic aromatic hydrocarbons (PAHs) and PAH-free fractions. All fractions were tested for mutagenicity by the Ames system. The highest dose-dependent increase in revertant colonies was found for the 4-7 ring PAH-fraction when tested with Salmonella typhimurium TA 98 and TA 100. These results are compatible with data obtained in in-vivo tests by previous investigations. The mutagenicity of these fractions in the absence of the oxygenase was negligible.
一辆乘用车（汽油发动机）的汽车尾气冷凝物被分离成含有2 - 3个环的馏分、含有4 - 7个环的多环芳烃（PAHs）馏分和不含PAH的馏分。所有馏分都通过艾姆斯试验系统进行了致突变性测试。当用鼠伤寒沙门氏菌TA 98和TA 100进行测试时，发现4 - 7环PAH馏分的回复菌落数随剂量增加最高。这些结果与先前研究在体内试验中获得的数据一致。在没有加氧酶的情况下，这些馏分的致突变性可忽略不计。
