类风湿关节炎和传染性单核细胞增多症中的抗中间丝抗体、抗角蛋白抗体和抗核周因子
Anti-intermediate filament antibodies, antikeratin antibody, and antiperinuclear factor in rheumatoid arthritis and infectious mononucleosis.
作者信息
Kataaha P K, Mortazavi-Milani S M, Russell G, Holborow E J
出版信息
Ann Rheum Dis. 1985 Jul;44(7):446-9. doi: 10.1136/ard.44.7.446.
Abstract
Sera from patients with rheumatoid arthritis (RA), patients with infectious mononucleosis (IM), and blood donors were tested by indirect immunofluorescence for the presence of antikeratin antibody (AKA), antibody to cytoskeletal intermediate filaments of prekeratin or vimentin type (AIFA) and antiperinuclear factor (APF). In 81.9% of the RA sera and 92.5% of the IM sera AIFA of IgM class was found at titres up to and in some cases exceeding 1/160. In blood donors the incidence of AIFA was 26%, at titres not exceeding 1/20. AKA and APF, always of IgG class, were found in 54.2% and 73.6% of rheumatoid sera. A weak correlation was found in RA between the incidence of AIFA and APF. AKA was not present in either IM or blood donor sera, and APF was found in only 2.5% and 3.2% of IM or blood donors respectively.
摘要
采用间接免疫荧光法检测类风湿关节炎（RA）患者、传染性单核细胞增多症（IM）患者以及献血者血清中的抗角蛋白抗体（AKA）、角蛋白前体或波形蛋白型细胞骨架中间丝抗体（AIFA）和抗核周因子（APF）。在81.9%的RA血清和92.5%的IM血清中发现IgM类AIFA，其滴度高达且在某些情况下超过1/160。在献血者中，AIFA的发生率为26%，滴度不超过1/20。AKA和APF均为IgG类，分别在54.2%和73.6%的类风湿血清中被发现。在RA中，AIFA和APF的发生率之间存在弱相关性。IM血清和献血者血清中均未检测到AKA，APF分别仅在2.5%的IM血清和3.2%的献血者血清中被发现。
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本文引用的文献
1
Antibody to intermediate filaments of the cytoskeleton.抗细胞骨架中间丝抗体。
Ann Rheum Dis. 1982 Feb;41(1):69-73. doi: 10.1136/ard.41.1.69.
2
Myositis autoantibody inhibits histidyl-tRNA synthetase: a model for autoimmunity.肌炎自身抗体抑制组氨酰 - tRNA合成酶：自身免疫模型
Nature. 1983;304(5922):177-9. doi: 10.1038/304177a0.
3
Induction of anti-intermediate filament antibody in rabbits experimentally infected with Trypanosoma brucei brucei.
Immunology. 1984 Jul;52(3):423-6.
4
Antibody to intermediate filaments of the cytoskeleton in the sera of patients with acute malaria.急性疟疾患者血清中针对细胞骨架中间丝的抗体。
Clin Exp Immunol. 1984 Jan;55(1):177-82.
5
Antibodies to cytoplasmic intermediate filaments in rheumatic diseases.
J Rheumatol. 1983 Aug;10(4):558-62.
6
In vitro induction of anti-intermediate filament antibody in lymphocyte cultures by Epstein-Barr virus.
Immunol Lett. 1982 Oct;5(4):203-5. doi: 10.1016/0165-2478(82)90135-3.
7
Messenger RNA is translated when associated with the cytoskeletal framework in normal and VSV-infected HeLa cells.在正常细胞和感染水泡性口炎病毒（VSV）的海拉细胞中，信使核糖核酸（mRNA）与细胞骨架框架结合时会被翻译。
Cell. 1981 Jan;23(1):113-20. doi: 10.1016/0092-8674(81)90276-2.
8
Reactivity of serum antibodies to the keratin layer of rat esophagus in patients with rheumatoid arthritis.类风湿关节炎患者血清抗体对大鼠食管角质层的反应性。
Arthritis Rheum. 1983 Apr;26(4):494-9. doi: 10.1002/art.1780260407.
9
Antiperinuclear factor and keratin antibodies in rheumatoid arthritis.类风湿关节炎中的抗核周因子和角蛋白抗体。
Ann Rheum Dis. 1981 Jun;40(3):263-6. doi: 10.1136/ard.40.3.263.
10
All classes of intermediate filaments share a common antigenic determinant defined by a monoclonal antibody.所有中间丝蛋白类别都共享一个由单克隆抗体定义的共同抗原决定簇。
Cell. 1981 Dec;27(3 Pt 2):419-28. doi: 10.1016/0092-8674(81)90383-4.
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