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哮喘治疗指南和药物选择的综述,重点关注运动性支气管收缩。

A review of guidelines and pharmacologic options for asthma treatment, with a focus on exercise-induced bronchoconstriction.

机构信息

Assistant Professor, School of Pharmacy and Health Professions and School of Medicine, Department of Family Practice, Creighton University, Omaha, NE.

出版信息

Phys Sportsmed. 2013 Sep;41(3):50-7. doi: 10.3810/psm.2013.09.2024.

DOI:10.3810/psm.2013.09.2024
PMID:24113702
Abstract

Asthma affects millions of individuals worldwide. Exercise-induced bronchoconstriction is common in patients diagnosed with asthma, but may also occur in patients without chronic asthma. Patients with isolated exercise-induced bronchoconstriction may require pretreatment with inhaled short-acting β-agonists prior to exercise. Patients diagnosed with asthma can achieve good control of the symptoms of exercise-induced bronchoconstriction with appropriate treatment of underlying chronic asthma. Current guidelines suggest staging patients with asthma based on severity of symptoms and initiating therapy according to their stage. Pharmacotherapy for asthma management consists of both quick-relief medications (short-acting β-agonists) as well as maintenance, or long-term control, medications (inhaled corticosteroids, long-acting β-agonists, leukotriene receptor antagonists, cromolyn, and theophylline).

摘要

哮喘影响着全球数以百万计的人。运动诱发性支气管收缩在被诊断患有哮喘的患者中很常见,但也可能发生在没有慢性哮喘的患者中。患有孤立性运动诱发性支气管收缩的患者可能需要在运动前预先吸入短效β-激动剂。诊断为哮喘的患者可以通过适当治疗潜在的慢性哮喘来实现对运动诱发性支气管收缩症状的良好控制。目前的指南建议根据症状的严重程度对哮喘患者进行分期,并根据其分期启动治疗。哮喘管理的药物治疗包括急救药物(短效β-激动剂)和维持或长期控制药物(吸入皮质类固醇、长效β-激动剂、白三烯受体拮抗剂、色甘酸钠和茶碱)。

相似文献

1
A review of guidelines and pharmacologic options for asthma treatment, with a focus on exercise-induced bronchoconstriction.哮喘治疗指南和药物选择的综述,重点关注运动性支气管收缩。
Phys Sportsmed. 2013 Sep;41(3):50-7. doi: 10.3810/psm.2013.09.2024.
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Long-term management of asthma.哮喘的长期管理
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Medical Therapy for Asthma: Updates from the NAEPP Guidelines.哮喘的医学治疗:来自 NAEPP 指南的更新。
Am Fam Physician. 2010 Nov 15;82(10):1242-51.
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Exercise-induced bronchoconstriction: diagnosis and management.运动诱发性支气管收缩:诊断与管理。
Am Fam Physician. 2011 Aug 15;84(4):427-34.
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Management of asthma in children.儿童哮喘的管理
Am Fam Physician. 2001 Apr 1;63(7):1341-8, 1353-4.
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New strategies in the medical management of asthma.哮喘医学管理的新策略
Am Fam Physician. 1998 Jul;58(1):89-100, 109-12.
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Drug therapy of childhood asthma.儿童哮喘的药物治疗
Indian J Pediatr. 2001 Sep;68 Suppl 4:S12-6.
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[Status of leukotrienes in the pathophysiology of asthma. Necessity for antileukotrienes treatment].[白三烯在哮喘病理生理学中的地位。抗白三烯治疗的必要性]
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Treatment options for the management of exercise-induced asthma and bronchoconstriction.运动诱发哮喘和支气管痉挛的治疗选择。
Phys Sportsmed. 2010 Dec;38(4):74-80. doi: 10.3810/psm.2010.12.1828.

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